Oncotype DX Misses on Breast Cancer Risk in Black Women Accuracy of 21-gene recurrence score worse compared with white women Jan 21, 2021
Not Just BRCA: Large Studies ID Other Key Breast Cancer Risk Genes Implications for screening and other risk-management strategies, researchers say Jan 20, 2021
Preop RT Flunks Test in Borderline Pancreatic Cancer Chemotherapy alone judged efficacious but not chemoradiation Jan 20, 2021
Drug Hits Target in Advanced Biliary Cancer Responses in up to a third of patients with FGFR inhibitor infigratinib Jan 19, 2021
Liquid Biopsy Predicts Colon Cancer Relapse Months Before CT Test for ctDNA outperformed existing biomarker, may help guide therapy Jan 17, 2021
New Target to Attack in Stomach Cancer PFS, OS improved with fibroblast growth factor receptor inhibitor in non-HER2 disease Jan 16, 2021
Ethics Consult: Refuse Treatment for Dictator? MD/JD Weighs In You voted, now see the results and an expert's discussion Jan 15, 2021
Copay Assistance Programs Help Patients but Confuse Them Too Insurers keep track of their use and in some cases won't apply them to patient deductibles Jan 13, 2021
Nuanced View of Oral Sex, HPV+ Oropharyngeal Cancer Age at first oral sex, 'intensity,' number of partners all influence risk Jan 13, 2021
Is This Really Cancer? Movement builds to classify Gleason 6 prostate lesions as nonmalignant Jan 09, 2021
Most Women Satisfied With 'Going Flat' After Mastectomy Lack of surgeon support key factor in later dissatisfaction, study shows Jan 08, 2021
Medicare's 'Most Favored Nation' Drug-Pricing Rule in Limbo Rule affecting Part B drugs was to take effect Jan. 1 but was stopped by federal court orders Jan 07, 2021
Targeted Combo Fails in EGFR-Mutant NSCLC Osimertinib-bevacizumab no better than osimertinib alone Jan 07, 2021
Baby Boys Get Cancer From Mom During Birth Report highlights potential fetal implications of undiagnosed maternal cervical cancer Jan 06, 2021
PARP Inhibitors Linked With Blood Cancer Risk Incidence of MDS/AML under 1%, but further investigation warranted as indications broaden Dec 28, 2020
Young-Onset Esophageal Cancer Rapidly Increasing Physicians should be on the alert for younger patients with dysphagia, researchers urge Dec 16, 2020
Add-On HDAC Inhibitor No Help in Breast Cancer PFS, OS similar to endocrine therapy alone for advanced HR+ disease Dec 15, 2020
Broader Role for PARP Inhibitors in Breast Cancer? Responses in tumors with somatic or germline mutations related to HRD Dec 14, 2020
Online Tool Refines Individual Risks in Breast Cancer RSClin incorporates 21-gene recurrence score with tumor grade, size, and more Dec 13, 2020
Doctor-Patient Discord in Reporting Radiation Toxicity Physicians underrecognized substantial symptoms in more than half of patients Dec 11, 2020
Non-Hodgkin Lymphoma: Bispecific Antibodies Impress in Refractory Disease Odronextamab, epcoritamab surpass 90% response threshold in early trials Dec 11, 2020
Adjuvant Palbociclib Fails in Early, High-Risk Breast Cancer No iDFS benefit with 1 year of CDK4/6 inhibition following neoadjuvant chemotherapy Dec 10, 2020
Chemo-Free Combo Boosts PFS in First-Line CLL PI3K-delta-based regimen also topped chemoimmunotherapy in relapsed setting Dec 08, 2020
Novel Agent Active in Refractory CML Asciminib doubles molecular response versus bosutinib after two or more prior lines of therapy Dec 08, 2020
High-Risk Prostate Cancer Patients Can Wait 6 Months for Surgery: Study Can be considered low priority procedure during COVID-19 pandemic, researchers say Dec 08, 2020
Gene Therapy Stops Bleeding in Hemophilia Single injection had durable effectiveness, study showed Dec 08, 2020
Chemotherapy Improved TNBC Survival in Older Women Benefits noted in both node-negative and -positive disease, as well as for those with a comorbidity score greater than 0 Dec 08, 2020
Tranexamic Acid May Hurt Head Trauma Survival for One Key Group Cheap antifibrinolytic given en route to hospital safe overall in registry Dec 07, 2020
Fixed-Duration Ibrutinib-Venetoclax Promising in First-Line CLL DFS at 1 year reaches 95% in patients with undetectable MRD Dec 06, 2020
CRISPR-Based Tx Offers Hope in Tough-to-Treat Blood Disorders Success with investigational use of gene editing in sickle cell disease, beta-thalassemia Dec 06, 2020
Blood Cancers and COVID-19: 'A Medically Vulnerable' Group Patients with hematologic malignancies and SARS-CoV-2 face higher risks for infection, death Dec 06, 2020
JAK Inhibitor Wins in Second-Line Chronic GVHD Twice as many patients achieved a response at week 24 Dec 05, 2020
Sickle Cell Disease Tied to Worse COVID-19 Outcomes Black patients seem to be at higher risk for certain COVID-19 complications, death Dec 05, 2020
Three-Drug Regimen Reduces Myeloma Treatment Burden Efficacy maintained with addition of SQ daratumumab to pomalidomide, dexamethasone Dec 04, 2020
Bone Marrow Improves Healing With ACL Grafts MRI confirms better outcomes than with allograft alone in randomized study Dec 04, 2020
FDA OKs 'Game Changer' Radiotracer for Prostate Cancer PET imaging drug detected metastasis at initial diagnosis, outperformed standard for PSA recurrence Dec 01, 2020
Study Reassures on MS Patients' Breast, Colorectal Cancer Risk But higher incidence of other cancers in Canadian data Nov 25, 2020
Potential New Option in Aggressive, Ultra Rare Sarcoma Highly durable responses with nab-sirolimus in malignant PEComa Nov 21, 2020
Cellular Therapies Promising in Advanced Synovial Sarcoma Two different strategies yield impressive results in patients with recurrent or metastatic disease Nov 20, 2020
Tiny Lung Micronodules in Bone Sarcoma Not Even a Tiny Problem? Five-year survival no worse in patients with micronodules under 5 mm Nov 20, 2020