Dual Targeted Tx a 'Meaningful' Option in BRAF-Mutant Glioma One-third of glioblastoma patients responded to dabrafenib-trametinib Apr 12, 2021
More Benefit With Taxane for Aggressive Metastatic Prostate Cancer Higher clinical benefit rate with front-line cabazitaxel versus androgen receptor inhibitor Apr 12, 2021
Triple-Negative Breast Cancers Not All the Same Histology tied to treatment response, outcomes Apr 12, 2021
A Win for Nivolumab as Preoperative Therapy for Lung Cancer Pathologic CR rate 12 times higher with the addition of anti-PD-1 agent to chemo Apr 11, 2021
Immunovirotherapy Shows Promise in Pediatric High-Grade Glioma Small study showed responses in 11 of 12 patients Apr 11, 2021
Nivolumab Alone Prevails in Resected Melanoma Adding ipilimumab in adjuvant setting failed to improve relapse-free survival Apr 11, 2021
Mixed Results for Immunotherapy in Metastatic Prostate Cancer Combination trial missed response endpoint but exceeded historical results Apr 11, 2021
Practice-Changing Results in Metastatic Uveal Melanoma Bispecific T cell-engaging tebentafusp reduces survival hazard by 50% Apr 10, 2021
Add-On PI3K Inhibitor Wins in Relapsed, Indolent NHL Adding copanlisib to rituximab also doubled CR rate, with manageable toxicity Apr 10, 2021
From VIPIT to VITT: Thrombosis and COVID Vaccines More data support link between adenovirus vector vaccines, blood clotting, and low platelets Apr 09, 2021
Complications Common in Excision of Retained Cervix After Hysterectomy Occur in almost 40% of procedures, cancer in 18% of cases Apr 09, 2021
Ethics Consult: Stop Treatment for Costly Patient? MD/JD Weighs In You voted, now see the results and an expert's discussion Apr 09, 2021
Can a COX-2 Inhibitor Boost Disease-free Survival in CRC? Large trial tested addition of the agent to standard FOLFOX Apr 06, 2021
No Cancer Risk With Commonly Used Blood Pressure Meds Largest analysis yet but definitive data remain elusive Apr 05, 2021
Anti-PD-L1 Flops in Locally Advanced Head and Neck Cancer No PFS benefit from adding avelumab to chemoradiation, hazard ratio favored placebo Apr 02, 2021
A Win for Adjuvant Immunotherapy in Esophageal Cancer And other highlights from the Society of Surgical Oncology's virtual 2021 meeting Mar 31, 2021
Triage System Gets High Marks for Ovarian Cancer Debulking Surgery Key factors predicted threefold higher risk of 90-day mortality with primary surgery Mar 26, 2021
HIPEC Combo Doubles PFS in Advanced Ovarian Cancer Cisplatin/paclitaxel boosts outcomes without increasing complications in registry study Mar 26, 2021
Combo Tx Active in Recurrent, Platinum-Resistant Ovarian Cancer Ixabepilone plus bevacizumab yielded responses in a third of patients Mar 26, 2021
Vaccines and Rare Clotting Disorders: What's the Link? Causal relation appears possible, but evidence still indicates it's extremely rare Mar 25, 2021
Model: Give COVID-19 Vaccine to All Patients Before Surgery Prioritizing surgical patient population could avert more COVID deaths Mar 25, 2021
Marrow Cell Stimulator to Treat Alzheimer's Disease? Unusual approach pans out in mid-stage trial Mar 24, 2021
Op-Ed: Blood Cancer Patients Need More COVID Vax Answers Patients are left wondering, "will I be protected?" Mar 24, 2021
Safety Reassurance for Major Class of Diabetes Drugs Pooled trial data show no link to breast cancer Mar 24, 2021
Little Benefit With Adjuvant Therapy for High-Risk Endometrial Cancer Chemo prevented relapse but did not improve survival, no benefit from radiotherapy Mar 23, 2021
Androgen Receptor Inhibitor Active in Endometrial Cancer SGO: Apatinib for platinum-resistant ovarian cancer, pembrolizumab for advanced vulvar cancer Mar 22, 2021
Hormonal IUD Shows Promise in Early Endometrial Cancer Regression seen in 82% of women with precancerous lesions Mar 21, 2021
Small Molecule Inhibitor Shows Promise in Resistant Ovarian Cancer Responses in 37% of patients with AVB-500, higher without prior bevacizumab Mar 21, 2021
Op-Ed: Primary Care and Specialty Ping Pong Let's put an end to bureaucratic medicine and treat the patient in front of us Mar 21, 2021
Is MIS Viable for Interval Debulking in Ovarian Cancer? Retrospective study compared approach versus open surgery after neoadjuvant chemotherapy Mar 21, 2021
PARP Inhibitor Tops Chemo for Recurrent BRCA Ovarian Cancer Modest improvement in PFS with rucaparib but worse outcome for reversion mutation Mar 20, 2021
Practice-Changing Trial in Second-Line Endometrial Cancer Pembrolizumab plus lenvatinib improved median OS by nearly 7 months versus chemotherapy Mar 19, 2021
Class of Cancer Drug Linked to Aneurysms, Artery Dissections Database analysis finds more reports than expected with antiangiogenic drugs Mar 18, 2021
Acupuncture Tops Usual Care for Pain in Cancer Survivors Two types of acupuncture proved superior, with one better than the other Mar 18, 2021
C3 Inhibitor Prevails in Trial of Rare Hemoglobinuria Improvement in hemoglobin, transfusion independence with pegcetacoplan for PNH Mar 17, 2021
Time to Revisit Distant Nodal Status in Breast Cancer Curability? Comparable survival for distant and regional nodal involvement, when treated similarly Mar 16, 2021
Holding tPA for All DOAC Users Not the Way to Go, Stroke Docs Say Clinical conundrum could be solved by a point-of-care DOAC test Mar 15, 2021
Whole-Genome Sequencing Makes a Case in Leukemia Study More actionable alterations detected in myeloid malignancies versus cytogenetics Mar 10, 2021
Study Confirms Risk-Adapted CRS Prophylaxis for Acute Leukemia Tocilizumab reduced severe cytokine release syndrome in children, young adults Mar 09, 2021
New Guideline Lowers Age to Begin Colorectal Cancer Screening Update comes as incidence has doubled in people under 50 Mar 09, 2021
