Blinatumomab-Chemo Consolidation a 'New Standard' in MRD-Negative B-ALL Phase III study showed 58% reduction in the risk of death versus chemo alone Dec 13, 2022
Pediatric Hodgkin Lymphoma Survivors Experience Accelerated Epigenetic Aging Data from St. Jude cohort show higher rates of neurocognitive impairment Dec 13, 2022
Direct-Acting Antivirals Linked to Improved Outcomes in Chronic Hepatitis C All-cause mortality rate significantly lower in treated versus untreated group Dec 13, 2022
Durable Platelet Response in Immune Thrombocytopenia With Efgartigimod Glycoprotein receptor inhibitor produces four times as many responses as placebo Dec 12, 2022
Black Patients Less Likely to Get Advanced Treatments for PE Also less likely for patients on Medicare and Medicaid Dec 12, 2022
AML Study Suggests Intensive Chemo Unnecessary Before Allo-HCT Similar outcomes if patients went directly to transplant or received intensive salvage first Dec 11, 2022
Talquetamab Offers New Hope in Relapsed/Refractory Multiple Myeloma Bispecific antibody achieves "incredible" response rates over 70% in heavily pretreated patients Dec 11, 2022
Ibrutinib Makes Its Case for First-Line Treatment in Mantle Cell Lymphoma Standard-of-care autologous transplant fails to prove superior to BTK inhibitor alone Dec 11, 2022
Rigid In-Hospital Diet Offers No Advantage in Patients After HSCT "We should eliminate these silly neutropenic diets," expert says Dec 10, 2022
Higher Brain Cancer Risk After CT Exam in Childhood Study suggests one radiation-induced brain cancer expected per 10,000 persons receiving a head CT Dec 09, 2022
Less Is More Wins Again: Avoiding Node Dissection in Early Breast Cancer First comparison of targeted sentinel node assessment shows no difference in recurrence rates Dec 09, 2022
Adding AKT Inhibitor Doubles PFS in Advanced, HR-Positive Breast Cancer In phase III trial, capivasertib benefited patients with or without AKT pathway alterations Dec 09, 2022
Oral SERD Tops Fulvestrant for PFS in ER-Positive Breast Cancer Camizestrant also led to meaningful PFS improvements in those with detectable ESR1 mutations Dec 09, 2022
Pharmacogenomic Results Clear to Young Cancer Patients' Families But few guardians shared these results with other care providers Dec 09, 2022
Small Study Shows Most Crohn's Patients With Anal Cancer Survived 15 of 24 were alive and cancer free at 5.5 years of follow-up Dec 09, 2022
Continuing CDK4/6 Inhibitor Beyond Progression No Help in Metastatic Breast Cancer Prior therapy, baseline mutations confound results; "intriguing" benefit with PD-L1 inhibitor Dec 09, 2022
Pausing Endocrine Therapy for Pregnancy Safe in Early Breast Cancer Study suggests no increased risk of cancer recurrence versus historical control Dec 09, 2022
T-DXd Continues Winning Streak in Metastatic, HER2-Positive Breast Cancer Trastuzumab deruxtecan improves survival in second- and later-line settings Dec 08, 2022
Neoadjuvant T-DXd Active in HER2-Low Breast Cancer Response rates on the order of 58-68%, with or without endocrine therapy Dec 08, 2022
Can Just Minutes of Daily Activity Prolong Life? Benefits included all-cause, heart, and cancer-related mortality risk reduction Dec 08, 2022
Everolimus Fails Again as Adjuvant Therapy for High-Risk Breast Cancer No improvement in the overall analysis but a hint of benefit in premenopausal patients Dec 08, 2022
Assay Predicts Breast Cancer Patients Who Will Benefit From Ovarian Suppression Low score suggests improved outcomes with ovarian suppression plus adjuvant endocrine therapy Dec 07, 2022
First-Line CDK4/6 Thumps Chemo in Aggressive, Advanced Breast Cancer Doubling of PFS could be death knell for combination chemotherapy in difficult-to-treat subgroup Dec 07, 2022
MRI-Targeted Biopsy for Prostate Cancer Reduces Risk of Overdiagnosis Though at the cost of delayed diagnosis of some clinically significant cancers Dec 07, 2022
Metastasis 'Doorway' May Lead to Racial Disparities in Breast Cancer Density of cellular complex after neoadjuvant therapy tied to cancer subtypes, may be targetable Dec 07, 2022
Cost Savings With Pharmacist-Driven Substitutions of Oncology Biosimilars Regional clinical pharmacists helped community oncology practices navigate logistics, financials Dec 07, 2022
Xeljanz Cancer Risks Detailed New paper provides full results from ORAL Surveillance trial Dec 07, 2022
I'm a Neurologist, Hear Me Roar If I wasn't believed when seeking care, what chance do non-physicians have? Dec 06, 2022
Decoding Cancer A conversation with Harold Varmus, MD, who received the Nobel Prize in Physiology or Medicine in 1989 Dec 06, 2022 podcast
Can Oncologists Reduce the Suicide Risk in Their Prostate Cancer Patients? Barriers exist in identifying risk, but strategies are available Dec 06, 2022
Aging U.S. Population a Challenge for Oncologists Older patients will have different care goals, preferences, geriatric oncologist says Dec 05, 2022
Year in Review: Acute Lymphoblastic Leukemia New ways to use CAR T-cell therapy and treatment de-intensification strategies Dec 05, 2022
To Combat Opioid Epidemic, Step Up Safe Prescribing Practices, Expert Urges Overprescribing a continuing problem, Benjamin Davies tells urologists Dec 02, 2022
Pre-Op Axitinib Helps for Partial Nephrectomy of Complex Renal Tumors Approach in small ongoing trial resulted in reduction in tumor size and complexity Dec 02, 2022
Sequential Gemcitabine/Docetaxel Promising in NMIBC After BCG Relapse But patients with BCG-refractory disease may be better suited for cystectomy Dec 02, 2022
New IDH1 Inhibitor Wins FDA Approval for Acute Myeloid Leukemia Olutasidenib led to a 35% response rate in a study of adults with previously treated AML Dec 02, 2022
Still Using Medical Jargon? Prepare to Be Misunderstood Survey shows just how often individuals misinterpret common medical phrases Dec 01, 2022
Metastasis-Directed Therapy May Delay ADT in Advanced Prostate Cancer Surgery or radiation delayed initiation of systemic therapy by 18 months Nov 29, 2022
Life and Death in 12 Hours ICU nurse Christin Thankachan on providing comfort during life's darkest moments Nov 29, 2022 podcast
