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Rheumatology

News, opinions and meeting coverage in rheumatology.

An empty prescription bottle laying on its side.

Slow Steroid Tapering Succeeds in SLE

Flare rates were significantly lower with gradual withdrawal than with low-dose maintenance

An x-ray image of erosive osteoarthritis of the hands.

Effective Treatments for Hand Osteoarthritis: The Search Goes On

Hydroxychloroquine not effective as disease-modifying drug for erosive hand OA, trial confirmed

A close up of a Heartmate 3 left ventricular assist device

Skin Rash Should Be a Huge Red Flag for LVAD Recipients, Group Says

New phenomenon suggests perils of not performing biopsy in time

A bottle and tablet of Rinvoq (upadacitinib) over an x-ray image of a spine with ankylosing spondylitis

Rinvoq Shows Promise in Spine Disease

1-year results in ankylosing spondylitis demonstrate efficacy for JAK inhibitor upadacitinib

Sagittal magnetic resonance images of psoriatic arthritis in the ankle region above a Stelara (ustekinumab) needle.

Target TNF or IL-12/23 in Psoriatic Arthritis?

Both TNF inhibitors and ustekinumab were effective in real-world use

A close up of a vial of methotrexate and a syringe in a man's hand

New ACR Rheumatoid Arthritis Guideline: Emphasis on Methotrexate

Many RA patients succeed with optimized use of the DMARD before adding another medication

A senior woman massages her painful arthritic hand

Pain Persists in RA, Even Without Inflammation

At 5 years, one-third of patients with rheumatoid arthritis still had "unacceptable" pain

A senior Asian woman sits on her couch experiencing knee pain.

Osteoarthritis: A Link With Parkinson's?

Inflammation may contribute to both joint and nerve degeneration

EULAR over a computer rendering of human body parts with the major joints glowing red

Secukinumab Shows Promise for Kids With Arthritis

More than 90% responded at week 12, study showed

EULAR over a computer rendering of human body parts with the major joints glowing red

Personalized Algorithm Helps Guide Rituximab Retreatment

For ANCA-associated vasculitis, fixed retreatment not needed if naive B cells reappear

EULAR over a computer rendering of human body parts with the major joints glowing red

IVIG a Winner for Dermatomyositis

Pivotal phase III trial shows clear efficacy

EULAR over a computer rendering of human body parts with the major joints glowing red

Nintedanib Slows Decline in RA-Associated Interstitial Lung Disease

Similar results to original larger trial seen in post-hoc analysis

EULAR over a computer rendering of human body parts with the major joints glowing red

Oral JAK 1 Inhibitor Eases Spine Inflammation in Ankylosing Spondylitis

Treatment with filgotinib resulted in significant improvements compared with placebo

EULAR over a computer rendering of human body parts with the major joints glowing red

Even Exposure to Passive Smoking Increases Risk of RA

Disease onset was earlier in women exposed to smoky rooms during childhood

EULAR over a computer rendering of human body parts with the major joints glowing red

Rituximab a Hazard in RA Patients With COVID

Poor outcomes were fourfold higher among rituximab users than for those on TNF inhibitors

A photo of a vial of Methotrexate for injection next to a syringe

Methotrexate Impairs COVID Vax Response

Can extra vaccine doses or discontinuing drug benefit patients with immune-mediated diseases?

A man's hand with psoriatic arthritis over a box of Ilumya (tildrakizumab-asmn) for injection.

Plaque Psoriasis Drug Shows Promise for Psoriatic Arthritis

Monoclonal antibody targets the IL-23 p19 subunit

A Stelara auto injector needle over a grid of close up psoriasis images.

For Safety, One Biologic a Winner in Psoriasis, Psoriatic Arthritis

Lower hospitalization rates compared with other biologics or small molecule therapies

'Talents' Land U.S. Researcher in Prison

Ohio MD pleaded guilty to lying on grant applications, planned to share research with China

A Taltz (ixekizumab) auto injector pen over a photo of a mans back, his spine highlighted in red

Stopping IL-17 Drug for Axial Spondyloarthritis? Expect Spinal Flares

But low disease activity regained if treatment restarted

A close up of a fresh modern surgical suture.

Op-Ed: Why the COVID Vaccine Didn't Work for Me

Millions of transplant patients need to be informed that they may not get sufficient protection

An illustration of a brain filled with lightbulbs, one is burning brightly, the others are dark.

The Death of One Little Girl Helped Millions

A case more than 35 years ago has spurred discoveries ever since

FDA ADCOMM oral avacopan over a medical illustration of vasculitis over a photo of a persons skin with purpura from vasculiti

FDA Panel to Weigh Avacopan's Fate for ANCA Vasculitis

Agency staff called out "interpretability" of phase III trial results ahead of Thursday's meeting

A photo of Carrie Ann Inaba

'Dancing With the Stars' Judge Carrie Ann Inaba's Autoimmune Diseases

TV host takes leave of absence

Bags of fentanyl tablets seized by the Drug Enforcement Agency

ED Docs Split Over Fentanyl Analogue Schedule 1 Extension

Will it save lives or prevent drug users from seeking help?

An artist rendition of fecal microbiota capsules

Results Disappoint for Fecal Transplant in Arthritis

But interest persists in targeting the gut-joint axis in psoriatic arthritis

A computer rendering of a human pelvis and spine, the sacroiliac joints and spine are highlighted in red

Delayed Diagnosis Common in Spinal Ailment

Typical 7-year delay after symptom onset leaves patients at risk for irreversible damage

New Side Effect From mRNA COVID Vaccines?

Surprise finding in Israeli case series

An MRI image of a perianal transsphincteric fistula

Perianal Involvement in Crohn鈥檚 Disease: How Bad for Prognosis?

Poor outcomes noted, especially with severe phenotype

A young woman touches the butterfly rash on her face

In Lupus, Even Minor Changes in Disease Activity Matter

One-unit increase in disease activity score raised mortality risk by 22%, study showed

NKF over a computer rendering of kidney disease

Pegloticase Safe for Dialysis Patients With Gout

Significant drop in monthly ESA dose seen after treatment, too

A Tremfya (guselkumab) syringe with the packaging box over a man's hand with enthesitis and psoriatic arthritis

For Enthesitis in Psoriatic Arthritis, Target IL-23

Targeted agent provides relief for many PsA patients

A close up of a woman clutching her stomach highlighted in red

Refractory IBD: The Case for Doubling Up on Drugs

Meta-analysis suggests select patients can avoid surgery

A close up of a man鈥檚 hand with psoriatic arthritis over a bottle of Rinvoq (upadacitinib) tablets

JAK Inhibitor Promising in Psoriatic Arthritis

Oral agent noninferior to adalimumab in joint symptoms

A computer rendering of monoclonal antibodies

FDA Panel Unhappy With Novel OA Pain Drug

Latest setback for troubled osteoarthritis biologic

Very high magnification micrograph of granulomatosis with polyangiitis and ANCA-associated granulomatous vasculitis.

Serious Infections Still Common in Vasculitis

Cyclophosphamide induction was riskier than rituximab

A close up of a mature African-American man massaging his aching hand

What to Tell Patients With Rheumatic/Musculoskeletal Diseases About COVID Vaccines

New guidance from the American College of Rheumatology

A world map in the Robinson projection with meridians and parallels grid over a micrograph of giant cell arteritis

Vasculitis Rates Rise With Earth's Latitude

Highest rates for giant cell arteritis seen in Scandinavia, lowest in Hong Kong

A bottle of Xeljanz (tofacitinib) tablets 5 mg over a computer rendering of ulcerative colitis

Game Changer for Ulcerative Colitis Patients Failing Anti-TNF?

JAK inhibitor helped when biologic didn't

The packaging of Taltz (ixekizumab) injection

Don't Stop Taltz in Psoriatic Arthritis

Significantly more patients relapsed, and more quickly, after withdrawal

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