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General Rheumatology

News, opinions and meeting coverage in rheumatology.

EULAR over a computer rendering of human body parts with the major joints glowing red

Even Exposure to Passive Smoking Increases Risk of RA

Disease onset was earlier in women exposed to smoky rooms during childhood

EULAR over a computer rendering of human body parts with the major joints glowing red

Rituximab a Hazard in RA Patients With COVID

Poor outcomes were fourfold higher among rituximab users than for those on TNF inhibitors

'Talents' Land U.S. Researcher in Prison

Ohio MD pleaded guilty to lying on grant applications, planned to share research with China

A close up of a fresh modern surgical suture.

Op-Ed: Why the COVID Vaccine Didn't Work for Me

Millions of transplant patients need to be informed that they may not get sufficient protection

FDA ADCOMM oral avacopan over a medical illustration of vasculitis over a photo of a persons skin with purpura from vasculiti

FDA Panel to Weigh Avacopan's Fate for ANCA Vasculitis

Agency staff called out "interpretability" of phase III trial results ahead of Thursday's meeting

A photo of Carrie Ann Inaba

'Dancing With the Stars' Judge Carrie Ann Inaba's Autoimmune Diseases

TV host takes leave of absence

A computer rendering of a human pelvis and spine, the sacroiliac joints and spine are highlighted in red

Delayed Diagnosis Common in Spinal Ailment

Typical 7-year delay after symptom onset leaves patients at risk for irreversible damage

New Side Effect From mRNA COVID Vaccines?

Surprise finding in Israeli case series

An MRI image of a perianal transsphincteric fistula

Perianal Involvement in Crohn鈥檚 Disease: How Bad for Prognosis?

Poor outcomes noted, especially with severe phenotype

NKF over a computer rendering of kidney disease

Pegloticase Safe for Dialysis Patients With Gout

Significant drop in monthly ESA dose seen after treatment, too

A Tremfya (guselkumab) syringe with the packaging box over a man's hand with enthesitis and psoriatic arthritis

For Enthesitis in Psoriatic Arthritis, Target IL-23

Targeted agent provides relief for many PsA patients

A close up of a woman clutching her stomach highlighted in red

Refractory IBD: The Case for Doubling Up on Drugs

Meta-analysis suggests select patients can avoid surgery

A close up of a man鈥檚 hand with psoriatic arthritis over a bottle of Rinvoq (upadacitinib) tablets

JAK Inhibitor Promising in Psoriatic Arthritis

Oral agent noninferior to adalimumab in joint symptoms

Very high magnification micrograph of granulomatosis with polyangiitis and ANCA-associated granulomatous vasculitis.

Serious Infections Still Common in Vasculitis

Cyclophosphamide induction was riskier than rituximab

A close up of a mature African-American man massaging his aching hand

What to Tell Patients With Rheumatic/Musculoskeletal Diseases About COVID Vaccines

New guidance from the American College of Rheumatology

A world map in the Robinson projection with meridians and parallels grid over a micrograph of giant cell arteritis

Vasculitis Rates Rise With Earth's Latitude

Highest rates for giant cell arteritis seen in Scandinavia, lowest in Hong Kong

A bottle of Xeljanz (tofacitinib) tablets 5 mg over a computer rendering of ulcerative colitis

Game Changer for Ulcerative Colitis Patients Failing Anti-TNF?

JAK inhibitor helped when biologic didn't

Vials of Actemra (tocilizumab) for injection over a microscope image of leukemia cells

Study Confirms Risk-Adapted CRS Prophylaxis for Acute Leukemia

Tocilizumab reduced severe cytokine release syndrome in children, young adults

A man doubled over in pain holds his aching foot

Combo Therapy Boosts Response in Uncontrolled Gout

"Markedly higher" rate than with pegloticase alone

A vial of Entyvio (vedolizumab) for injection over a computer rendering of ulcerative colitis

Vedolizumab Tied to Lower Risk for Serious Infections in Ulcerative Colitis

But positive association versus TNF inhibitors not seen in Crohn's disease

The packaging and syringe of Kineret (anakinra) over a microscope image of uric acid crystals

Anakinra for Gout Flares: Is There a Role?

IL-1 blockade was not superior to triamcinolone, but does have advantages

A chest radiograph showing diffuse alveolar hemorrhage

Lung Hemorrhage in Lupus: Which Patients Die?

Risk factors include older age, longer disease duration, infection, and certain treatments

The chemical structure of avacopan over a microscope image of Antineutrophil cytoplasmic antibodies (ANCA)

Avacopan for ANCA Vasculitis: A New Treatment Paradigm?

Remission rates not inferior to prednisone -- the "unthinkable" achieved

A computer rendering of monoclonal antibodies

Monoclonal Antibody Highly Effective in Phase III Psoriasis Trial

Beats ustekinumab, but main side effect was oral candidiasis

A box of Xeljanz (tofacitinib) tablets over a background of thumbs down icons

JAK Inhibitor Misses Endpoint in Safety Study. Now What?

Major blow to popular class of oral rheumatology drugs

Two bottles of Colchicine tablets over an illustrated background of COVID-19 viruses

Colchicine for Early COVID-19? Trial May Support Oral Therapy at Home

But some find science-by-press-release troubling

CCC over a computer rendering of colitis

IBD and COVID: Kids Do Well

International registry shows older age, comorbidities are risks; anti-TNF might protect

A collection of copay cards issued by pharmaceutical companies

Copay Assistance Programs Help Patients but Confuse Them Too

Insurers keep track of their use and in some cases won't apply them to patient deductibles

A computer rendering of a blood clot

Staying Safe in Lupus: Monitor Hydroxychloroquine Levels

Limit the retinopathy risk while maintaining anti-thrombotic protection, study suggests

A photo of President Donald Trump signs an executive order in the Oval office

Medicare's 'Most Favored Nation' Drug-Pricing Rule in Limbo

Rule affecting Part B drugs was to take effect Jan. 1 but was stopped by federal court orders

PET scans of a person showing severe vasculitis

PET Scans Reveal Vascular Inflammation

In giant cell arteritis, imaging confirmed clinical response

A mature woman with a butterfly rash on her face

Who Flares When SLE Patients Stop Hydroxychloroquine?

Flares more likely among minorities, younger patients, and those taking steroids

AIBD over a photo of a woman with her hands on her abdomen highlighted in red

Ozanimod a Winner in Ulcerative Colitis

S1P receptor modulator effective for both induction and maintenance

A bottle of Colchicine capsules in front of a vortex of $100 bills

Colchicine Approval Took a Huge Toll on CMS

As centuries-old drug is explored for COVID-19, study details the price of approval

A close up of a man鈥檚 foot with his big toe swollen from gout

Lifestyle Mods May Head Off Gout

Four addressable factors appear key

ACR over a computer rendering of a human skeleton with the joints of the fingers highlighted in red

TYK2 Inhibition Promising in Psoriatic Arthritis

Phase II study found significant benefits for two doses of novel agent

A close up of a man clutching his abdomen which is highlighted in red

More Evidence Early Mortality Persists in IBD

Canadian study shows treatment advances haven't erased lifespan deficit

ACR meeting

COVID Complications Common with Rheumatic Disease

Adverse outcomes included acute kidney injury and congestive heart failure

ACR over a computer rendering of a human skeleton with the joints of the fingers highlighted in red

Rinvoq for RA: Benefits Persist Beyond 1 Year

Manufacturer's extension study shows no loss of clinical response

EADV over a collage of venereology/dermatology icons

Nonsteroidal Topical, Nanodrug Active in Psoriasis

Selected presentations from the European Academy of Dermatology and Venereology meeting

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