Upadacitinib, Abatacept Go Head to Head in RA And the winner is... both, depending on whether efficacy or safety is the main criterion Oct 14, 2020
Depression and Biologic Use in Arthritis: Chicken or Egg? Relationship appears to be bi-directional, researchers say Oct 02, 2020
Novel Biologic Promising in Mid-Stage Scleroderma Trial Significant differences seen at week 24 for the agent versus placebo on background therapy Sep 28, 2020
COVID-19 Storms: Bradykinin In, Cytokine Out? Papers poke holes in cytokine storm as gene expression study offers a new theory Sep 11, 2020
Mepolizumab Offers Relief for Chronic Sinus Trouble Anti-IL5 biologic cut polyp size, need for surgery in chronic rhinosinusitis with nasal polyps Sep 10, 2020
Capsaicin Injection Improves Knee OA Pain Investigational treatment targets capsaicin receptor to inactivate local pain fibers Sep 06, 2020
Novel Form of Muscle Relaxant Shows Benefit Tolperisone may help pain from acute back spasms without causing drowsiness Sep 05, 2020
Joint Effusion Protective in Hand OA Unlike synovitis, which was linked with both pain and progression Sep 03, 2020
Al Roker's Shoulder Replacement "Today" co-host and weatherman battles osteoarthritis pain Aug 25, 2020
Lupus Anticoagulant Tied to COVID Thrombosis Small study suggests consideration of therapeutic anticoagulation Aug 12, 2020
Few Risks for Sjogren's Patients With Joint Surgery Transfusion rates raised but no increase for infection, revision, or mortality Jul 30, 2020
Tocilizumab Raises GI Risks in Rheumatoid Arthritis Double the risk of one rare but potentially deadly event compared with use of TNF inhibitors, large Swedish study found Jul 22, 2020
Targeting IL-23 Relieves Multiple Symptoms in PsA Both enthesitis and dactylitis improved with guselkumab treatment in psoriatic arthritis Jul 21, 2020
Colchicine Shows Promise in COVID-19 Patients, With Caveats Clinical effects need further investigation, authors urge Jun 24, 2020
Muscle Relaxer Rx Doubled Over 12-Year Span Spike in prescriptions among older adults particularly concerning, researchers note Jun 24, 2020
Gout: Methotrexate May Enhance Pegloticase Response In small study, uric acid levels were reduced to near undetectable levels in almost 80% of patients Jun 09, 2020
Psoriatic Arthritis: Outcomes Similar for Cosentyx and Humira Primary endpoint of superiority for secukinumab over adalimumab not met in a phase IIIb trial Jun 08, 2020
Voclosporin Beats Standard of Care in Lupus Nephritis High rates of response seen even among difficult-to-treat Hispanic patients Jun 05, 2020
Avacopan Superior to Steroids in ANCA Vasculitis Greater rates of remission and improved renal function seen with oral C5a receptor antagonist Jun 04, 2020
Another IL-6 Blocker Succeeds in Rheumatoid Arthritis Effective in patients with moderately to severely active disease in a phase III trial Jun 03, 2020
EULAR 2020: What to Expect Cancelled due to pandemic but extensive menu of virtual learning planned Jun 02, 2020
High-Dose Vitamin D Disappoints for Preventing Crohn’s Recurrence No benefit seen despite substantial increase in serum 25-OH-D May 27, 2020
Biologics Don't Increase Melanoma Risk... Probably Meta-analysis offers some reassurance, but leaves room for doubt May 20, 2020
IL-17A Blockers Succeed in Spine Disease Secukinumab and ixekizumab best placebo for ankylosing spondylitis May 13, 2020
Study Backs Cytokine Targeting for COVID-19 Tx Interrupting host inflammatory response shows promise May 08, 2020
CellCept Succeeds in ANCA Vasculitis Benefits, however, for only one serotype of antineutrophil cytoplasmic antibodies, study found May 07, 2020
Do You Believe in HCQ for COVID-19? It Will Break Your Heart Milton Packer believes advocacy of the drug is practicing politics, not medicine May 06, 2020
Rheumatoid Arthritis: Biologic Dose Cuts Feasible Majority of patients who achieved remission, low disease activity could lower biologic intake without flaring Apr 30, 2020
Gout and Sleep Apnea: It's Complicated Risk is increased with comorbidities such as heart failure and renal impairment Apr 28, 2020
Gout Raises Risk of Heart Failure in Older Adults Results support need for interventions to reduce the excess risk in this population, researchers say Apr 21, 2020
Allopurinol in Gout: Is There a Mortality Benefit? Hopes were that a new meta-analysis could provide an answer Apr 16, 2020
HCQ Plus Azithromycin: A Dangerous Combination? Antimalarial drug appears safe alone; whether it's effective in COVID-19 still unclear Apr 14, 2020
Guselkumab a Hit in Phase III for PsA Primary endpoints met in two large trials in psoriatic arthritis for IL-23 inhibitor Apr 10, 2020
IL-17A/F Inhibitor a Winner in Spine Disease Targeting both cytokines had rapid, sustained benefits in ankylosing spondylitis Apr 09, 2020
Psoriasis IL-23 Biologic Maintains Efficacy in 2-Year Trial Phase III trial looked at risankizumab (Skyrizi) Apr 08, 2020
Complement Biomarkers Help Predict Lupus Cell-bound complement activation products were more sensitive than traditional biomarkers Mar 24, 2020
Rheumatologists: On the COVID-19 Front Line Experience with rheumatic drugs may help in the most severe cases Mar 22, 2020
Respiratory and GI Symptoms? Don't Rule Out COVID-19 Commentary also urges PPE use given potential fecal shedding of virus Mar 17, 2020
In Vasculitis, Beware of Infection Serious and laboratory-confirmed infection risks elevated for years in ANCA-associated vasculitis Mar 13, 2020
