Study Supports More Inclusive Clinical Trials With Broader Eligibility Criteria No difference in adverse events, clinical benefit, OS for patients with or without waivers Jun 27, 2024
Is Cholesterol Denialism Pseudoscience or Appropriate Medical Care? Calling an end to debate rarely serves the advancement of knowledge Jun 20, 2024
Retract Now: Negating Flawed Research Must Be Quicker Incentives and streamlined processes can prevent the spread of incorrect science Jun 18, 2024
Community-Based Interventions for Opioid Overdoses Fail to Reduce Deaths in Trial "Game plan" established to get evidence-based practices into the real world, researcher says Jun 16, 2024
New Tricuspid Interventions Launched into 'Broken' System Having the technology reach the right patients is a major challenge in the real world Jun 08, 2024
Can Mitral Valve Innovators Dig Themselves Out of a Rut? Current transcatheter mitral valve replacement devices a poor match for clinical need Jun 06, 2024
Paxlovid Trial Flops for COVID Pneumonia Small study found no decrease in mortality among inpatients in three countries Jun 06, 2024
Docetaxel Tied to Less Taxane Neuropathy in Black Breast Cancer Patients Dose-limiting toxicity has been linked with worse outcomes specifically in this population Jun 05, 2024
GLP-1 Agonists in Adolescents and Young Adults; Benefits of Cancer Drug Trials Also in TTHealthWatch: early diagnosis and treatment of COPD and asthma May 25, 2024 podcast
Cancer Clinical Trial Participation May Not Actually Improve Survival, Study Says Meta-analysis suggests survival benefits disappeared after accounting for biases, confounders May 22, 2024
More Patients Participate in Cancer Treatment Trials Than Previously Estimated Study calculates rate at 7.1%, higher than historical estimate of less than 5% May 13, 2024
Lack of Clinical Trial Availability Tied to Worse Prostate Cancer Mortality "It's a trend we really don't want to see," researcher says May 06, 2024
Closing Gender-Based Disease Disparities Starts in the Lab Women must have a seat at the table in deciding what type of research to pursue Apr 27, 2024
FDA Warning Letters Detail Controversy at Psychiatric Institute Two letters - one to a psychiatrist - follow reports of a trial participant's suicide Apr 02, 2024
Trump Avoids Talk of Father's Alzheimer’s; Teens Smell Like Goats; AI Drugs a Bust? Health news and commentary from around the Web gathered by staff Mar 22, 2024
Patients and Doctors Push Back Against the Harsh Side Effects of Cancer Drugs "If the patients are not taking the drug, then it's not going to work" Feb 06, 2024
As Investors Pile Into Psychedelics, Idealism Gives Way to Pharma Economics Challenges abound for the burgeoning sector Feb 05, 2024
The Healthcare Landscape Is Changing. Our Regulatory Practices Should Too. Closer collaboration between FDA and CMS is the need of the hour Jan 22, 2024
Physicians Don't Always Understand the FDA Approval Process, Survey Finds Most preferred two or more randomized trials as evidence required for approval Jan 19, 2024
IG Live January 17: From Long COVID Symptoms to Solutions Leading long COVID researcher Ziyad Al-Aly, MD, discusses new research Jan 16, 2024
Benefits of Myeloma Regimens in the Real World Fall Well Short of Trials Survival 75% worse compared with outcomes seen in registrational studies Dec 10, 2023
No Laughing Matter: Women's Health Is Not a 'Women's Issue' It's about time the U.S. focused on women's health research Nov 26, 2023
Communicating Uncertainty About Drugs Granted Accelerated Approval An education gap exists about "the possibility that these drugs might not work," says expert Nov 13, 2023 video
Competing Incentives of the FDA's Accelerated Drug Approval Experts weigh drug availability against possible suboptimal outcomes Nov 09, 2023 video
ChatGPT Created a Fake Dataset With Skewed Results Findings raise concerns about the ease of generating false medical evidence Nov 09, 2023
What if Trial Participants Knew Their Contributions Were for Naught? A call for enforcing trial reporting requirements Oct 28, 2023
IG Live October 23: Life in the Fast Lane With FDA's Accelerated Approvals Experts share their perspectives on the increasingly controversial FDA pathway Oct 19, 2023
Modern Medicine Forgot to Confirm It Works for Women, Too An excerpt from Cat Bohannon's new book, Eve Oct 15, 2023
After-the-Fact Informed Consent for a Clinical Trial? It Can Work in Some Situations Sometimes it's not practical to perform the study any other way Oct 11, 2023
Sotorasib's Confirmatory Data in NSCLC Unreliable, Says FDA Panel But agency doesn't plan to immediately push for KRAS inhibitor's withdrawal Oct 05, 2023
FDA Staff Highly Skeptical of Confirmatory Data on KRAS Inhibitor in NSCLC Reviewers see potentially tiny PFS benefit with sotorasib, raise concerns over "systemic bias" Oct 04, 2023
FDA Relents, Approves Novel Antidepressant After Many Rejections Gepirone extended-release approved after nearly 2 decades of trying Sep 28, 2023
FDA Reviewers Have Concerns About Artificial Womb Trials in Humans The Pediatric Advisory Committee will discuss if data support a safe first-in-human trial Sep 15, 2023
It's High Time for Gender-Inclusive Clinical Research Health decisions must account for all types of bodies and identities Jul 18, 2023
Xeljanz Edges Humira Just a Bit for Real-World RA Patients, Study Suggests Australian researchers perform "target trial emulation" to compare popular drugs Jun 30, 2023
Stanford Study of Paxlovid for Long COVID Stopped Early Enrollment was halted earlier than planned after interim analysis Jun 30, 2023
At $20K, Stem Cell Eye Injections May Also Cost Patients Their Sight Patients claim vision got worse after "clinical trial" at Florida stem cell clinic Jun 26, 2023
Rates of Consent Withdrawal in Cancer Trials Low but Not 'Trivial' Factors associated with greater likelihood of withdrawal included Hispanic ethnicity, older age Jun 22, 2023
How to Overcome the Catch-22 in Precision Medicine Research Improving the patient experience will go a long way May 31, 2023
