番茄社区

Psychiatry

News, opinions and meeting coverage in psychiatry.

In Cocaine Users Think About Levamisole

HOUSTON -- Half of a group of cocaine users tested positive for levamisole, a potentially hazardous veterinary drug that cocaine dealers often use to prepare street product, investigators reported here.

Muscle Massage Rubs Out Inflammation

Heavily stressed muscles responded to massage therapy with a variety of biologic changes associated with reduced inflammation, analysis of tissue specimens showed.

OCD in Adulthood Traced to Cues in Childhood

Rituals and sensory hypersensitivities in a child may be early warning signs of adult obsessive-compulsive disorder (OCD), according to the results of two studies from Israel.

FDA Panel Split Over Inhaled Antipsychotic

WASHINGTON -- An FDA advisory panel punted on the question of approval for an inhaled version of the antipsychotic drug loxapine (Adasuve) to treat agitation in bipolar and schizophrenic patients, despite the risk for respiratory side effects.

Side Effects of Loxapine Aerosol Raise FDA Concerns

WASHINGTON -- Although staccato loxapine (Adasuve) appears to be effective in calming schizophrenic and bipolar patients, concerns remain about the drug's pulmonary side effects, according to a review by FDA staff members.

ADHD Drug Helpful in Adult Depression

Phase II trial results suggested that a stimulant drug approved to treat attention deficit-hyperactivity disorder may improve cognitive function in adults with major depression, its manufacturer said.

Low-Dose Zolpidem Gets FDA Okay for Wee-Hours Awakening

A new formulation of the insomnia drug zolpidem tartrate (Ambien) has been approved to treat middle-of-the-night awakenings followed by difficulty returning to sleep, the FDA said.

Acetaminophen OD More Deadly if Taken in Stages

Acetaminophen overdoses were more likely to be fatal if patients consumed a series of high doses spread over the course of a day rather than downing, say, a bottle of pills at one time, outcomes among patients admitted to a specialized liver center showed.

Use of Psych Drugs Up, Women Biggest Users

One American in five takes psychiatric medication for conditions such as depression and anxiety, and use of the drugs is more common among women, researchers found.

Jumpy Legs in Parkinson's Likely Not RLS

Patients with early Parkinson's disease were more likely to have a movement disorder called leg motor restlessness than true restless legs syndrome, a study found.

Linezolid Toxic With Prozac, Other SSRIs, FDA Warns

The FDA has issued an updated statement on the potential for serious central nervous system toxicity when patients taking serotonergic psychiatric drugs are treated with the antibacterial agent linezolid (Zyvox).

High Blood Pressure May Spark Facial Nerve Pain

Patients with hypertension appear to carry a higher risk for developing trigeminal neuralgia, a Taiwanese study showed.

FDA Blocks Sale of Supplements for Parkinson's and Alzheimer's

WASHINGTON -- The FDA filed a permanent injunction against two Minnesota companies that distributed amino acid products marketed as treatments for Parkinson's disease, Alzheimer's disease, and a number of other neurological disorders.

Medtronic Infusion Pump Recalled

Battery problems with two of Medtronic's SynchroMed II implantable infusion pumps have forced the company to recall them, according to the FDA, although the recall only affects products not yet implanted.

FDA Warns Against High-Dose Citalopram

Citing increased risk of cardiac arrhythmias and a lack of therapeutic benefit associated with high doses of the SSRI citalopram hydrobromide (Celexa), the FDA has reduced the recommended maximum to 40 mg/day.

APA: Munchausen by Proxy Victims Not All Kids

HONOLULU -- Although most reported cases of Munchausen-by-proxy syndrome involve children, adults can also be victims, a researcher said here.

Lab Notes: Red Wine Before Radiation and Red Clover for Hair Loss

Red is the color of the day, as components of red wine and red clover lead this week's Lab Notes, but the blues get their turn in the spotlight, too, as depressed people outshine cheerier folks in some elements of decision making.

No More Infant Dose of OTC Acetaminophen

Over-the-counter drug makers have announced that they will no longer produce acetaminophen in concentrated infant drops; liquid acetaminophen products for children under 12 will be sold only in a 160 mg/5 mL concentration.

FDA Panel: Keep ECT Devices as High Risk

GAITHERSBURG, Md. -- The FDA should continue to regulate electroconvulsive therapy (ECT) machines as high-risk devices for treating depression and most other conditions for which ECT is typically used, members of the agency's Neurological Devices Advisory Committee agreed.

Early Sexual Abuse Linked to Later Psychosis

Children who are sexually abused, particularly if the abuse involves penetration, are at risk for later developing a psychotic disorder, an Australian case-control study found.

ACG: GI Docs Should Ask About Abuse

SAN ANTONIO -- Gastroenterologists may want to be attuned to signs of possible abuse or trauma among their patients, a researcher suggested here.

FDA Panel Looks at Trials of Devices to Treat Depression

GAITHERSBURG, Md. -- An FDA advisory panel met Friday to discuss how to analyze trials designed to test devices used to treat depression, but didn't offer the FDA any clear-cut guidance.

Mild Mania Often Accompanies Major Depression

A high proportion of people with major depression may actually have a "hidden" form of bipolar disorder, according to a population-based study.

Antidepressants Not Recommended for Autism

Selective serotonin reuptake inhibitors (SSRIs) can't be recommended for treating autism in children or adults at this point, according to a Cochrane review.

Diagnostic Nerve Blocks Costly -- and Controversial

While some guidelines recommend two diagnostic nerve blocks before radiofrequency treatment for chronic low back pain, a randomized trial showed greater success without use of the prior blocks.

APA: Field Testing to Begin in July for DSM-5

NEW ORLEANS -- More than 10 years after the American Psychiatric Association (APA) began developing its fifth edition of the Diagnostic and Statistical Manual of Mental Diseases (DSM), the process is now moving smartly toward its planned 2013 conclusion, leaders of the effort said here.

ASCO: Cancer Survivors Get Benefit from Yoga

CHICAGO -- Gentle stretching, breathing, and other exercises in a regular yoga program may ease sleep and fatigue problems common among cancer survivors, a randomized trial found.

Handedness Linked to ADHD

Ambidextrous 5-year-olds are more likely to develop attention deficit-hyperactivity disorder symptoms later on as compared with right- and left-handed children, according to a study by a team of Swedish researchers.

The Top 10 Medical Advances of the Decade

From genome to hormones, doctors pick the top medical advances of the decade.

Ziprasidone Okayed for Bipolar Disorder

The FDA has approved another antipsychotic agent -- ziprasidone (Geodon) -- for maintenance treatment of bipolar I disorder as an adjunct to lithium or valproate.

Drop in Oxygen Saturation in Apnea Tied to Obesity

Obese patients may experience more severe blood oxygen desaturation during apnea and hypopnea events, researchers say.

Drug Combo Brings Better Pain Relief

For people with neuropathic pain, a combination of two commonly used drugs works better than either alone, researchers said.

FDA Panel Recommends Limited Use of Investigational Antipsychotic

SILVER SPRING, Md. -- An FDA advisory panel voted to recommend FDA approval for sertindole (Serdolect) to treat schizophrenia, but only for a subgroup of patients that the agency would have to define.

Nursing Homes Called 'Dumping Grounds' for Mentally Ill

BALTIMORE -- Young and middle-aged people with serious mental illnesses are increasingly being housed in nursing homes alongside elderly residents, Centers for Medicare and Medicaid Services data show.

Recall of Three Little Words Helps Quick Diagnosis of Mild Cognitive Impairment

ATLANTA -- Mild cognitive impairment can be determined in less than five minutes with a three-word memory test and a clock- drawing task, according to researchers here. The words are apple, penny, and table.

Oral Prednisolone and Naproxen (Aleve) Equal for Gout Pain

NIJMEGEN, The Netherlands, May 29 -- For the acute pain of monoarticular gout over four days, it's a tossup between oral prednisolone and naproxen (Aleve), a randomized trial found.

Neurochemical May Underlie Lack of Motivation in Psychosis

CAMBRIDGE, England -- The lack of motivation characteristic of schizophrenia and other psychoses may not be a result of long-term treatment or institutionalization, researchers here suggested.

Aripiprazole (Abilify) Potentially Useful for Treating Alcohol Dependence

FARMINGTON, Conn. -- The atypical antipsychotic aripiprazole (Abilify) modified the behavioral and physiological effects of alcohol in a small preliminary study.

Five SSRIs Endorsed as Effective for Obsessive Compulsive Disorder

LONDON -- Five antidepressants given for obsessive compulsive disorder all seem to confer twice the likelihood of modest symptom relief compared with placebo, found a systematic review.

Lung Cancer Risk of One Marijuana Joint a Day Equals Daily Pack of Cigarettes

WELLINGTON, New Zealand -- Smoking a single marijuana joint may be as carcinogenic to the lung as 20 tobacco cigarettes, researchers here calculated.

鈥�

62