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OB/Gyn

News, opinions and meeting coverage in obstetrics and gynecology.

Ondansetron Safe for Fetus, Study Affirms

Use of the antiemetic ondansetron during pregnancy was not associated with any adverse fetal outcomes, an observational study showed.

Contraception: Condoms Are King, Plan B Takes Hold

In the realm of contraception, the condom reigns supreme, but one in 10 have used emergency contraception such as Plan B, according to two reports on the contraceptive methods used by women of reproductive age in the U.S.

FDA Lowers Ambien Dosages

WASHINGTON -- Makers of sleep drugs containing zolpidem, including Ambien and Ambien CR, must cut the recommended dosages for women by half to reduce morning drowsiness, the FDA announced Thursday.

Metformin Role in Breast Cancer Still Unclear

SAN ANTONIO -- Clinical trials of the diabetes drug metformin in breast cancer yielded a few possible clues to anticancer activity but little else, according to a series of reports.

Effexor May Not Mix with Tamoxifen

SAN ANTONIO -- The antidepressant venlafaxine (Effexor), often given to breast cancer patients to treat the hot flashes associated with tamoxifen therapy, might reduce the effectiveness of the drug, a researcher said here.

Statins May Slow Inflammatory Breast Cancer

SAN ANTONIO -- Inflammatory breast cancer grew significantly more slowly in women who had a history of treatment with statin drugs, findings from a large retrospective review showed.

Repeat CT Scans May Up Breast Ca Risk in Young Women

CHICAGO -- A female teenager who undergoes multiple chest or cardiac CT studies may see her 10-year risk for breast cancer double, researchers said here.

'Scatter' Effects of Mammography Pose Little Risk

CHICAGO -- Scatter radiation from screening mammography is minimal, even to the thyroid, and results in negligible risk to the patient, researchers reported here.

Lupus Patients Tend to Skip Pap Tests

WASHINGTON -- Women with systemic lupus erythematosus do not appear undergo timely cervical cancer screening despite being at an increased risk for cervical dysplasia and HPV infection, researchers said here.

FDA Panel Wary on Making Bladder Control Drug OTC

WASHINGTON -- An FDA advisory panel on Friday voted against recommending making oxybutynin transdermal patch (Oxytrol) available over-the-counter for overactive bladder in women.

Colon Cancer Risk Rises After Endometrial Ca

LAS VEGAS -- A history of endometrial cancer at a younger age quadrupled the likelihood of a subsequent diagnosis of colorectal cancer, a retrospective analysis of administrative data showed.

Study Counters WHI on Risk of Hormones in Menopause

Hormone therapy may actually help the heart in some respects for newly menopausal women, a randomized trial showed, although the impact on hard outcomes like stroke and breast cancer still remains to be seen.

Drug Works in AI-Resistant Breast Cancer

SAN FRANCISCO -- A tamoxifen-like drug slowed progression of advanced breast cancer previously treated with a nonsteroidal aromatase inhibitor, results of a small Japanese trial suggested.

Afinitor Helps Breast Tx in Older Patients

SAN FRANCISCO -- Older patients with advanced breast cancer had significant improvement in progression-free survival when everolimus was added to exemestane, a new analysis of a randomized trial showed.

Young Women Skip Mammo After USPSTF Recs

SAN FRANCISCO -- Rates of screening mammography among women younger than 50 declined within 2 months of a negative recommendation by the U.S. Preventive Services Task Force (USPSTF) and have remained below baseline rates, according to a study reported here.

Device May Cut Re-Excision Rate in Breast Cancer

SAN FRANCISCO -- Re-excision after breast-conserving surgery occurred 50% less often with intraoperative margin assessment by a device that distinguishes cancer cells from normal tissue, results of a randomized study showed.

Lying Prone for Radiation Best for Breast Tx

Lying face down for radiation therapy lessens the amount of collateral damage to breast cancer patients' heart and lungs, researchers found.

Daily Cialis Alternative to On-Demand Drug

CHICAGO -- For men who don't respond to on-demand tadalafil (Cialis), a low daily dose may do the trick, researchers said here.

Chewable Viagra Gets Thumbs-Up in Mexico

CHICAGO -- Men thought a chewable version of sildenafil (Viagra Jet) made the drug work faster and longer, a Mexican study found.

Newest ED Drug Works in Less than Half Hour

CHICAGO -- The highly specific PDE5 inhibitor Avanafil may work in as little as 15 minutes after dosing, researchers said here.

Viagra from Online Sources Mostly Fake

CHICAGO -- Most of the sildenafil (Viagra) sold online is counterfeit and contains far less of the active ingredient than the real thing, researchers said here.

Persistence of Finasteride Side Effects Raised at Meeting

CHICAGO -- One of the topics under discussion among sexual medicine specialists, gathered here from around the world, is whether the sexual side effects of a hair-loss drug are long-lasting, according to a leader in the field.

NYC to Limit Baby Formula in Hospitals

By Labor Day, at least 27 hospitals in New York City will have implemented the main components of an initiative aimed at encouraging breastfeeding for new mothers.

NAMS Founder: WHI Wrong on HRT

A leader of the North American Menopause Society wants an independent review of all major publications from the Women's Health Initiative.

DSM-5: What's In, What's Out

PHILADELPHIA -- Reports here provided what may be the last public update on DSM-5, the next edition of American psychiatry's diagnostic guide, before it is formally released in May 2013.

Most DSM-5 Revisions Pass Field Trials

PHILADELPHIA -- Field trials of proposed new diagnostic criteria for many mental disorders showed that, for the most part, they were at least adequately reliable.

G Spot Comes Out of Hiding

That elusive sexual will-o'-the-wisp, the G spot, has been found. It just wasn't where anyone had looked.

FDA Warns of Clot Risk with Yaz, Other OCs

Labels for oral contraceptives that contain drospirenone will now note that studies have shown up to a threefold increased risk of blood clots compared with other birth control pills.

Doctors Say 45 Common Tests 'Overused'

Nine specialty groups have listed tests and treatments that are frequently overused, such as antibiotics for sinus attacks and CT scans for low back pain, in the first phase of a long-term project.

Extreme Obesity Adds More Risk in Hysterectomy

AUSTIN, Texas -- Increasingly severe obesity drives up complication rates after hysterectomy, and outcomes continually worsen with rising body mass index, according to results from a study reported here.

Circumcision Tied to Drop in Herpes, Too

SEATTLE -- African men who underwent circumcision not only reduced their risk of contracting HIV infection, they also were significantly less likely to be infected with herpes simplex virus-2, researchers reported here.

FDA Adds More Warnings for Lipitor, Crestor, and Zocor

WASHINGTON -- Statins may cause drug-drug interactions for patients taking drugs to treat HIV/AIDS or hepatitis C, according to a new statin warning from the FDA.

Komen Official Quits After Controversy

A vice-president at the Susan G. Komen for the Cure Foundation has resigned in the wake of the controversy surrounding the organization's decision -- since reversed -- to stop funding Planned Parenthood's breast cancer programs.

Epidural Plus Fever During Labor Put Baby at Risk

A temperature spike during labor with epidural analgesia may indicate serious risks for the baby in an otherwise low-risk delivery, researchers found.

Lack of Birth Control Common Among Teen Moms

About half of teenage mothers who didn't plan to get pregnant did not use contraception at the time they conceived, CDC researchers found.

Herpes Drugs Work, but Not Forever

Anti-herpetic agents reduce recurrence of herpes simplex-2 (HSV-2) symptoms but do not completely block subclinical shedding of virus, even at high doses, researchers reported.

RSNA: Growth Hormone May Help Heavy Women With Bone Problems

CHICAGO -- Premenopausal women who are obese may not be spared from osteopenia, as some research has suggested, but growth hormone therapy may help spur bone formation, researchers said here.

FDA Revokes Avastin Approval for Breast Cancer

WASHINGTON -- The FDA has announced that bevacizumab (Avastin) is no longer approved for the treatment of breast cancer; the Genentech drug retains its other indications and will remain on the market.

AMA Adopts Policies on Circumcision, Gun Safety

The American Medical Association (AMA) House of Delegates has adopted a number of new policies at its interim meeting, including policies on male circumcision, physician discussion of gun safety, and a new medical coding system that will go into effect in 2013.

Tampon Recall Stems from Bacterial Contamination

Kimberly-Clark has announced the recall of a number of Kotex brand tampon lots because of contamination with potentially life-threatening Enterobacter sakazakii.

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