Oral SERD Tops Fulvestrant for PFS in ER-Positive Breast Cancer Camizestrant also led to meaningful PFS improvements in those with detectable ESR1 mutations Dec 09, 2022
Continuing CDK4/6 Inhibitor Beyond Progression No Help in Metastatic Breast Cancer Prior therapy, baseline mutations confound results; "intriguing" benefit with PD-L1 inhibitor Dec 09, 2022
Pausing Endocrine Therapy for Pregnancy Safe in Early Breast Cancer Study suggests no increased risk of cancer recurrence versus historical control Dec 09, 2022
T-DXd Continues Winning Streak in Metastatic, HER2-Positive Breast Cancer Trastuzumab deruxtecan improves survival in second- and later-line settings Dec 08, 2022
Neoadjuvant T-DXd Active in HER2-Low Breast Cancer Response rates on the order of 58-68%, with or without endocrine therapy Dec 08, 2022
Everolimus Fails Again as Adjuvant Therapy for High-Risk Breast Cancer No improvement in the overall analysis but a hint of benefit in premenopausal patients Dec 08, 2022
Assay Predicts Breast Cancer Patients Who Will Benefit From Ovarian Suppression Low score suggests improved outcomes with ovarian suppression plus adjuvant endocrine therapy Dec 07, 2022
First-Line CDK4/6 Thumps Chemo in Aggressive, Advanced Breast Cancer Doubling of PFS could be death knell for combination chemotherapy in difficult-to-treat subgroup Dec 07, 2022
Metastasis 'Doorway' May Lead to Racial Disparities in Breast Cancer Density of cellular complex after neoadjuvant therapy tied to cancer subtypes, may be targetable Dec 07, 2022
Exercise During Chemo Shows Benefits for Cardiorespiratory Fitness However, patients who exercise after chemo also ultimately see benefits too Nov 21, 2022
RT After Breast-Conserving Surgery Shows No Survival Advantage Decades Later But "that's not the intent of radiation therapy," says outside expert Nov 18, 2022
Oral, Hormone-Free Med Reduces Hot Flashes in Breast Cancer Patients Q-122 was effective, well-tolerated in those on oral adjuvant endocrine therapy Nov 11, 2022
My Risk Revealed: A Confirmed BRCA2 Mutation My dad's cancer diagnosis offered me invaluable information Oct 30, 2022
Study Suggests Potential to Skip Surgery for Selected Breast Cancer Patients No recurrences in 2 years after pathologic complete response in TNBC, HER2-positive tumors Oct 26, 2022
Concurrent Boost During Hypofractionated RT Proves Its Worth in Early Breast Cancer Reduces treatment time, noninferior to conventional RT with sequential boost after lumpectomy Oct 26, 2022
Nerve-Freezing Technique Staves Off Post-Mastectomy Pain Percutaneous cryoneurolysis improved analgesia in a pilot study Oct 24, 2022
Mepitel Film Beats Standard for Stopping Radiation Dermatitis in Breast Cancer "The most improvement in skin toxicity that I have seen in many years," expert says Oct 19, 2022
Risk of Secondary Breast Cancer After Childhood Cancer Is Declining, Study Suggests Improvement credited to changes in chest RT, attenuated by use of pelvic RT, anthracyclines Oct 13, 2022
This One Risk Factor Dominates for Soft Tissue Sarcoma After Breast Cancer Risk is low but appears to have modifiable components Oct 13, 2022
Katie Couric's Breast Cancer The popular media personality is on a mission to raise awareness around dense breasts Oct 06, 2022
Hand Cooling, Compression Both Effective for Nerve Pain in Breast Cancer But access, cost, and tolerability may favor the latter option, said researcher Sep 14, 2022
Denosumab Halts Bone Loss From Ovarian Suppression, AIs for Breast Cancer Areal BMD increased when given at the start of maximal estradiol depletion therapy Sep 13, 2022
Targeted Combo Flops as First-Line Treatment in Advanced Breast Cancer No clinical benefit boost with anti-CD73 oleclumab added to durvalumab and chemo Sep 10, 2022
Antibody-Drug Conjugate Prolongs Survival in Metastatic Breast Cancer Positive outcome with sacituzumab govitecan leads to questions about ADC sequencing Sep 09, 2022
2 Years of Endocrine Therapy, 2 Decades of Protection From Metastatic Breast Cancer Tamoxifen protects low-risk premenopausal patients, goserelin helps high-risk patients Aug 31, 2022
Do Therapy-Related Hot Flashes in Breast Cancer Signal Worse Outcomes? Swedish study finds reduced DFS in women who used drugs for hot flashes Jun 22, 2022
Diabetes Threatens Long-Term Survival in Metastatic Breast Cancer 5-year survival rates were not affected, however Jun 13, 2022
Forego Radiotherapy for Women With Low-Risk Luminal A Breast Cancer? Study shows 5-year local recurrence rate of 2.3% with lumpectomy and endocrine therapy alone Jun 07, 2022
Trastuzumab Deruxtecan Ushers in New Treatment Era for HER2-Low Breast Cancer DESTINY-Breast04 extends agent's benefits to historically tough-to-treat disease Jun 05, 2022
Capivasertib-Fulvestrant Combo Ups Survival in ER+/HER2- Metastatic Breast Cancer But benefit seems to be predominantly in patients with PI3K/AKT/PTEN pathway alterations Jun 05, 2022
Sacituzumab Govitecan Boosts PFS in Late-Line HR+/HER2- Metastatic Breast Cancer "This may be something that really changes the lives of these women for the better," expert says Jun 05, 2022
Adjuvant Everolimus Fails to Stop Recurrence in Early High-Risk Breast Cancer More than half of everolimus-treated patients permanently discontinued treatment Jun 02, 2022
Prone Beats Supine Positioning for WBRT in Women With Large Breasts Prone position led to lower rates of moist desquamation May 27, 2022
Black Patients Often Never Given a Chance to Join Breast Cancer Trials But survey finds several actionable findings that could boost enrollment May 26, 2022
Vaginal Estrogen 'Underutilized' in Women With GSM After Breast Cancer Prescribing rate is half that of women with no breast cancer history May 13, 2022
Screening, Early Detection Remain Keys to Lower Cancer Mortality Presidential panel sets course to remove barriers, increase services, and improve uptake May 05, 2022
Young Cancer Survivors Face Higher Risk of Death From Second Malignancies Study finds 25% higher risk of secondary cancers versus general public, 84% higher risk of death May 04, 2022
Menstrual Cycles Point to Link Between Sex Hormones and Long QT Research suggests new tools for risk stratification and therapy May 01, 2022
DCIS Recurrence Often Represents a New Primary Breast Cancer Almost a fifth of cases unrelated to primary DCIS, raising questions about current treatment Apr 11, 2022
RT Prior to Mastectomy, Reconstruction Shows Promise U.K. study demonstrates low complication rates and good aesthetic results Apr 08, 2022
