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Nephrology

News, opinions and meeting coverage in nephrology.

ESC: Interatrial Shunting Safe in HFpEF, Pivotal Trial to Come

Device eases left-sided filling pressure, but to what clinical significance?

ESC: Tafamidis Cuts Deaths, Admissions in TTR Cardiac Amyloidosis

Plus clear advantage seen in 6-minute walk test

ESC: Xarelto Fails to Change Outcomes in Heart Failure

No death or hospitalization reduction seen in COMMANDER-HF

ESC: MitraClip Fails in Functional Mitral Regurgitation

No impact on hard outcomes in MITRA-FR randomized trial

Primary Prevention Headlines at ESC

Will aspirin, fish oil pan out in big trials?

Skeptical Cardiologist: Where Are My Generic Meds Made?

Valsartan recall prompts a look by Anthony Pearson, MD

'Test and Treat' Programs Reduce HIV Infections

Multi-disease attack shows benefits across the board

TAVR Growing Even in Younger Age Groups

National trends seen across ages through 2015 likely have continued

Tight BP Control Lowers Risk for Mild Cognitive Impairment

Data came from controversial SPRINT trial

Paying Cash at Walmart Often Cheaper than Medicare Copay

Heart drug analysis finds this especially with Medicare Advantage plans

Cancer Risk With Diabetes Higher in Women than Men

Authors recommend "sex-specific approach" to prevention and treatment

Afib Patch Test; Heart Failure and Genetics: It's PodMed Double T!

This week's topics include a patch to diagnose atrial fibrillation, USPSTF recommendations on nontraditional risk factors for heart disease, the role of genetics in congestive heart failure, and multivitamins and heart disease.

Verapamil Success for T1D; Bariatric Surgery Wait; Self-Monitoring Without Insulin?

News and commentary from the endocrinology world

Shorter Wait Times May Favor HCV-Infected Kidney Transplants

Long-term dialysis while waiting for uninfected kidney a larger risk

Proteinuria Flags Risk for Post-Op Kidney Injury

Even trace levels of urinary protein tied to elevated rate of acute renal impairment

SGLT-2 Inhibitors Tied to Lower All-Cause Mortality Risk

Head-to-head comparison with DPP-4 inhibitors also showed heart protection

'Artificial Pancreas' System Boosts In-Hospital T2D Control

Less time out of range, no increase in insulin or lows with fully-automated system

Early T2D Treatment in Youth Disappoints

Metformin, insulin didn't stop deterioration of beta-cells in adolescents with impaired glucose

TB Vaccine for T1D Study Stirs Controversy

Long-term data suggest BCG vaccine may alter immune attack

Intensive Treatment Doesn't Cost More

Therapy aimed at treating all organ targets extends life

Farxiga Lowers HbA1c in Type 1 Diabetes

Weight loss also accompanied better glycemic control

Eversense CGM Comes Out on Top for Accuracy in T1D

Dexcom G5 performed best in hypoglycemia

Sotagliflozin Tx Tied to HbA1c Reductions in T1D

But instances of diabetic ketoacidosis are a concern, expert says

GLP-1 Drug Boosts T1D Control

A1c, glucose, weight, blood pressure all improved in randomized trial

Basal Insulin Doesn't Cut Hypoglycemia Risk Vs NPH in T2D

Similar hypoglycemia-related emergency department and hospital admissions

Dual-Hormone Artificial Pancreas Ups T1D Glucose Control

Rapid insulin plus pramlintide also reduced glucose variability

180-Day Implantable CGM Deemed Safe in T1D Patients

The system's accuracy stabilized with longer use, researchers reported

Closed-Loop T1D Systems Show Promise

Omnipod, Diabeloop systems offer better glucose control than conventional treatment

Severity of Mom's Diabetes May Up Autism Risk in Their Kids

But GDM diagnosed after 26 weeks' gestation not associated with excess risk versus no diabetes

ADA's 2018 Meeting Spotlight Latest Trials

One of anticipated includes pediatric outcomes of RISE trial

Euro, U.S. Hypertension Guidelines Not So Different

BP guideline guru Suzanne Oparil, MD, weighs in

Europe Stands Pat on Hypertension Thresholds

ESC doesn't follow ACC/AHA on diagnostic cutoff, focuses on control rates

Do You Preach According to the Gospel of Saint Ablation?

Milton Packer calls on electrophysiologists to embrace rigorous evidence interpretation

Many with Metastatic Kidney Cancer Can Skip Surgery

Overall survival with single-agent sunitinib better than with resection

Pilot Study Hints at IABP Benefit for Some STEMI Patients

Trend toward better prognosis in those with persistent post-PCI ischemia

AACE 2018 Potpourri

Additional noteworthy research presented at AACE meeting

LAMA Tx Didn't Up Heart Disease Risk in COPD

Cardiovascular outcomes similar to placebo-treated patients

Novel Renal Denervation Catheters Showing Modest BP Reductions

The latest from sham-controlled Symplicity Spyral and Paradise trials

CPAP Lowered Heart Rate in Prediabetics with Sleep Apnea

Magnitude of reductions in comparable to beta-blockers, researchers say

Hypogonadal Men See Better Heart Health on Testosterone Tx

Fewer deaths due to MACE seen over 10 years versus controls

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