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AASLD

Efruxifermin Led to NASH Resolution, Fibrosis Improvement in Mid-Stage Trial

Both 50- and 28-mg doses improved fibrosis vs placebo, without worsening of NASH

Maralixibat Takes Out the Itch of Rare Liver Disease

Ileal bile acid transporter inhibitor could become second drug for PFIC

Odevixibat Shows 'Encouraging Results' for Kids With Alagille Syndrome

Significant improvements in itching, bile acid levels for rare, life-threatening liver disorder

Acamprosate Appears Safe for People With AUD and Liver Disease

Phase II data suggest drug is well-tolerated and can reduce cravings in this group of patients

Tenofovir, Vaccine Combo Eliminates Mom-to-Child HBV Transmission

100% success rate even without the use of hepatitis B immunoglobulin

BP Control Beneficial for Liver Transplant Recipients

Patients who kept their blood pressure under 140/90 mm Hg had better kidney function at 1 year

Earlier Terlipressin May Be Better for HRS-AKI in Acute-on-Chronic Liver Failure

More acute kidney injury reversals at 7 days and lower mortality with initiation at 12 hours

Low Carb Diet Boosts Weight Loss for Liver Transplant Recipients With Obesity

LCD also positively impacted patients' metabophenotype

Pandemic's Impact on Liver Disease in the Spotlight at Liver Meeting

A roundup of news from the AASLD annual meeting

Is Weight Protective for NAFLD Patients Undergoing Transplant?

UNOS data showed differences in waitlist removal, all-cause mortality based on obesity status

Hepatology Not Immune to Workplace Discrimination

Women, racial/ethnic minorities most likely to experience discriminatory behavior

Need for Liver Transplants Rising Sharply in Seniors

Post-transplant mortality still higher versus younger patients, but improving over time

'Concerning' Opioid Prescribing in Patients With Cirrhosis

PCPs more than twice as likely as gastroenterologists to prescribe opioids

How Do Patients With Cirrhosis Respond to the COVID Vaccine?

Italian researchers examine data in this understudied subset of patients

Blood-Based Biomarkers Prove Mettle in Liver Disease Diagnosis

Data part of initiative to qualify biomarkers to help diagnose fibrosis or NASH

FMT Benefits Last a Few Years in Severe Alcoholic Hepatitis Patients

More research needed to determine impact on clinical outcomes versus standard of care

Simvastatin-Treated Liver Donors May Aid Transplant Patient Outcomes

Improved graft survival versus placebo in small randomized trial

Iron Load in NAFLD Tied to Higher Liver Cancer Risk

Clinical surveillance of serum iron levels may be worth monitoring, researcher says

How Did the COVID Pandemic Affect Liver Transplant Outcomes?

There was an impact on patient survival rates, but researcher acknowledges several confounders

NASH Patients Are Entitled to a 'Bill of Rights'

Advocacy group encourages a "partnership" between clinicians and patients

Fewer Hepatitis C Patients Seeking Treatment of Late

Accelerated declines in 2020 only the latest in a downward trajectory

COVID-19 and MIS-C: Two Diseases, One Virus in Kids

Both clinical profiles and even outcomes varied, researcher says

Chronic Liver Conditions Raise Risk of Death in COVID-19 Patients

Alcohol appears to play major role, researcher says

How South Korea Avoided a COVID-19 Lockdown

Test, trace, treat and transparency key to controlling outbreak, expert reports

Trial Finds Semaglutide Resolves NASH in Many Obese Adults

But "unexpected" lack of improvement in fibrosis stage vs placebo

Reassuring New Data for Pregnant Women With Cirrhosis

Risk of liver complications may be much lower than previously reported

Kratom-Linked Hepatotoxicity on the Rise in the U.S.

Clinicians should be aware that the herbal supplement can cause liver injury, researcher says

HCV Combo Pill a Winner in Untreated Cirrhotic Patients

High SVR12 rate suggests 8-week treatment could be used for this population

Minorities Sicker than Whites at Liver Transplant Referral

Blacks had highest MELD scores at waitlist registration among racial-ethnic groups

Novel Thyroid Beta Receptor Agonist Cut LDL-C in NAFLD Patients

Small phase II study also found reductions in liver fat vs placebo

Regular Aspirin Use Tied to Reduction in HCC Risk

Significant benefit apparent after ≥5 years of use at average dose of at least 1.5 tablets/week

Do Patients with Chronic Liver Disease Face Higher DILI Risk?

Research suggests a link of which drug developers should be aware, expert says

Hepatitis C Treatment Works Well for Young Kids

Nearly all children treated with sofosbuvir/ledipasvir achieved sustained response

Pregnant Women at Risk for HCV Benefit from Universal Screen

Test deemed more efficient, cost-effective diagnostic approach versus risk-based screening

'De-Fatting' Tx May Give Discarded Livers New Life

Ex vivo perfusion system plus therapy reduced fat in steatotic livers

AASLD Poster Roundup: Gender, Insurance, Weight and Waitlists

Selections from poster sessions at the annual Liver Meeting

Liver Meeting to Focus on Practice Matters Along with Science

Topics range from 'day in the life' of a hepatology consultant to novel NASH therapies

Unlabeled Ingredients in 'Herbal' Supplements Seen Causing Liver Injury

Common culprits: body-building, weight-loss products

Experts Raise Red Flag over Fatty Liver Disease

Paints gloomy picture for population health, economy

PBC Drug Promising in New Setting

Lowers levels of enzyme in primary sclerosing cholangitis

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