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AAN

New Hints that Vitamin D Helps MS Patients

Two randomized trials miss endpoints but still strongly suggest benefit

Eteplirsen Boosts Dystrophin, Function in DMD

Details from 12 patients in Study 201/202 reported at AAN

Novel Parkinson Therapies Highlighted at AAN Meeting

Early results with gene therapy, new carbidopa-levodopa formulation featured

Thymectomy Effective for MG Patients Without Chest Tumor

Randomized trial confirms benefit from surgery

Older Kids With SMA Still Benefit From Nusinersen

But motor benefits more impressive in infants

More Botulism Cases Tied to Heroin 'Skin Popping'

Fifteen cases over 10-year period in El Paso, Texas

Novel Biologic Works for Episodic Migraine Prevention

But effect size small with erenumab, and questions about vascular risk remain

SMA Gene Therapy Promising in Early Results

12 children with spinal muscular atrophy hit motor milestones in phase I trial of AVXS-101

Daytime Sleepiness, Brain Pathology: A 2-Way Street?

Amyloid buildup may be both effect and cause of sleep-wake abnormalities in elderly

Lifestyle Program May Slow Cognitive Decline

At-risk seniors seem to benefit from nutritional guidance, vigorous exercise

Is 'No Evidence of Disease Activity' a Misnomer in MS?

Many patients still show signs of active disease despite meeting current NEDA criteria

Guideline: Emphasize Seizure Control to Save Lives

Tonic-clonic seizures tied to SUDEP risk, according to AAN/AES guideline

Seizure Risk After Sepsis Lasts for Years

Far above rates seen in non-sepsis patients, especially at younger ages

Cannabidiol Cuts Seizures in LGS Patients

Decreased appetite, sleepiness most common side effects

Fatigue, Leg Dysfunction Predict Multiple Sclerosis Progression

Both associated with subsequent conversion to secondary progressive MS

Female Athletes More Prone to Recurrent Concussion

Reason unclear, study leader calls for more research

Men with Children Sleep Fine; Women Not So Much

Men not bothered by their own snoring, either

Neurologic Problems Common in Ebola Survivors

Mechanism of persistent symptoms still unclear

Everolimus May Have Activity in Seizure Disorder

Drug reduced seizure frequency in tuberous sclerosis compared with placebo

Tysabri No Help in SPMS

Drug didnt reduce disability progression but may benefit upper limb function

Data Aired on Periodic Paralysis Drug

Trial results presented for drug approved last year

Novel Drug Bests Interferon at Halting MS Activity

Nearly half of patients on ocrelizumab achieved no evidence of disease activity (NEDA)

New Drug Eases Tardive Dyskinesia in Pivotal Trial

Tremors related to treatment for schizophrenia quieted by VMAT2 inhibitor

Gene Tx Offers Hope in Degenerative Brain Disorder

Treatment 'milestone' in childhood cerebral adrenoleukodystrophy

Transcranial Doppler May Pinpoint Concussion Sooner

Researchers test advanced ultrasound to measure brain blood flow

Nearly Half of Former NFL Players Show Signs of Brain Injury

MRI scans detect TBI markers in more than 40%

Botulinum Toxin Guidelines Overhauled

Strong evidence supports specific formulations in spasticity, chronic migraine

Once-Daily Epilepsy Tx Shows Promise

Eslicarbazepine non-inferior to twice-a-day carbamazepine

Seizure Drug May Help in MS Eye Disease

Phenytoin shows promise for slowing neurodegeneration in optic neuritis.

'Brain Code' Speeds Meds to Neuro Patients

Algorithm plus medication distribution system reverses herniation, lowers intracranial pressure.

An 80-Proof Antidote for MS Disability?

Patients consuming more of the hard stuff had lower EDSS scores.

'Sudden Adult Death' May Have Mitochondrial Origin

Some cases of unexplained sudden death can be traced to a common mitochondrial defect.

Increasing Tysabri Dosing Interval May Cut PML Risk

No sacrifice of efficacy seen in retrospective analysis.

Experts Gain Ground in CTE Diagnosis

NIH working group says perivascular tau deposition is hallmark feature of chronic traumatic encephalopathy.

Novel Drug for Cramping Shows Promise in Early Trial

Could benefit patients with MS spasticity and cervical dystonia.

Idebenone Slows Respiratory Decline in DMD

Antioxidant is thought to stimulate mitochondrial activity to preserve breathing ability.

TBI Patients Keep Cool With Induced Normothermia

Protocol linked to better temperature control and lower in-hospital mortality.

Guideline: Managing Unprovoked First Seizures in Adults

Anti-epileptic drugs may reduce risk of recurrence, joint AAN-AES guideline says.

Humans Beat Stroke Scales for ICH Prognosis

PHILADELPHIA -- Physicians and nurses in stroke units more accurately predicted outcomes in patients with intracerebral hemorrhage (ICH) compared with common prognostic scales, a researcher reported here.

'Sensory Tricks' in Dystonia Examined

PHILADELPHIA -- The mystery of how "sensory tricks" adopted by patients to relieve symptoms of dystonia work is beginning to be unraveled, research presented here suggested.

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