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News, opinions and meeting coverage in oncology/hematology.

Hippocampus-Sparing Radiation a New Option in Brain Mets Patients

Approach preserved cognitive function, but patient prognosis a key consideration

First-Line Anti-PD-1 Ups Survival for Advanced Head/Neck Cancer

Pembrolizumab, with or without chemo, tops current standard

Cetuximab Fails Twice vs Cisplatin for HPV-Related Oral Ca

Cetuximab resulted in more patient deaths across U.S., German studies

Liquid Biopsy Rules Out Relapse in HPV-Positive Oral Ca

Test had 100% negative predictive value

No 'Sound Science' Behind Avoiding Topical Agents Before RT

Increased dose to skin only seen when applying 'copious' amounts

SBRT Doubles 5-Year Survival in Oligometastatic Cancers

Most patients in phase II trial had up to three metastatic lesions

Alternative Therapies Popular With Sarcoma Patients

Drug-drug interactions still poorly understood

Inherited JAK3 Mutation May Up Head/Neck Ca Risk in African Americans

About 8% carry the single nucleotide polymorphism

Knowledge Gaps on HPV's Link to Head/Neck Ca for Docs in Training

Few are equipped to perform HPV vaccine counseling, study found

SSA Transition Safe, Effective for NETs

Long-term survival, cost-effectiveness examined in other studies

Molecular Profiling Can ID Cancer Risk in Thyroid Lesions

In lesions with atypia, different mutations confer higher and lower risks

Surveillance Appears Reasonable for Small pNETs

All patients with tumors

Surgery Improves Survival for most pNETs

Mortality odds 70%-80% lower for all but stage I disease

Docs Need to Discuss Money Matters with Cancer Patients

Breast cancer, older patients report high levels of "financial toxicity"

Survey: Cancer Patients Will Pay Anything for Treatment

Confirms what drug companies already knew

Frequent Basal Cell Cancers Sign of Broader Inherited Risk

Tripled rates of internal malignancies such as breast and prostate tumors

Study: Paclitaxel Best for HIV-Related Kaposi's Sarcoma

Other chemotherapies fall behind in resource-limited setting

Cancer Risk With Diabetes Higher in Women than Men

Authors recommend "sex-specific approach" to prevention and treatment

Multi-Flap Head and Neck Surgery: It's Complicated

Need for individualized assessment, discussion emphasized by meta-analysis

Lymphoma Risk with JAK Inhibitors for MPNs

Preexisting aberrant B-cell clone implicated

Quick Intervention Improves Care in Geriatric Cancer Patients

Randomized trial improved oncologist-patient communication

IMPACT Trial: Support for Targeted Cancer Tx Approaches

Survival doubled with therapy matched to tumor genetics

Pancreatic Ca Gets 20-Month Survival Boost

Aggressive post-surgery chemo regimen touted as new standard of care

Pre-Surgical CRT May Boost Survival in Pancreatic Ca

Further data needed to clarify best approach and who would benefit most

Rare Childhood Cancer Gets First Tx Advance in 30 Years

But impact unclear for U.S. rhabdomyosarcoma patients

Women Get Less Aggressive Tx for Head and Neck Ca

Registry data find that women are less likely to receive chemotherapy or radiation than men

Carvedilol Helps Protect Heart During PPGL Surgery

Med offers superior blocking for cardiac complications in pheochromocytoma

Better Specificity with Next-Gen Thyroid Gene Sequence Test

Afirma GSC seems to send fewer patients for surgical intervention

Exercise Cuts Hyperglycemia For Cancer Patients on Chemo

Pilot study hints at other benefits from walking program

Thyroid Nodule Location Predictive of Malignancy

Nodules in the upper pole more likely to be cancerous

Low PTH-Calcium Ups Risk for Long-Term Parathyroid Problems

Levels help guide patient management after thyroidectomy

CBT Tops Acupuncture for Treating Insomnia in Cancer Survivors

But both methods provide alternative to sleeping pills

Intravesical Gemcitabine Reduces Bladder Ca Recurrence

Could be more feasible than mitomycin C

Algorithm Helps Manage Fever

Pediatric cancer patients with non-neutropenic fever could benefit

Morning Break: Stolen Trump Records; Gyns in Trouble; Eye Cancer Cluster?

Health news and commentary from around the Web gathered by the 番茄社区 staff

'Time Is Muscle' When Reversing Facial Paralysis

Surgical technique uses thigh muscle to restore movement

Back to Work After Esophagectomy?

Only 40% had full occupational recovery by 1 year

Hepatitis C Treatments Reduce Transplants

Therapies also appear to reduce liver-related mortality

Europe Gets Updated HCV Tx Guidelines

EASL panel touts 'ease of use' of direct-acting antivirals

SIRT + Sorafenib = No Survival Bump in Liver Cancer

But clinical benefits suggested in certain patients with less severe disease

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