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Oncology/Hematology

News, opinions and meeting coverage in oncology/hematology.

A photo of the vials and packaging of Irinotecan hydrochloride.

Nanoliposomal Irinotecan Fails to Boost Survival in Treated Advanced Biliary Cancer

No difference in PFS, median OS favored control group

A computer rendering of a lung tumor.

Another KRAS Inhibitor Scores an Early Win in Advanced Non-Small Cell Lung Cancer

Half of patients responded, but editorialists call for new directions in therapy development

A photo through the doorway of the CT scanning room.

Middle-Age Man Presents With Necrotizing Mass on Nose

Rare condition can be deadly without early diagnosis and treatment

A scanning electron microscope image of a dendritic cell

Dendritic Cell Therapy Offers No Survival Advantage in Pleural Mesothelioma

Immunotherapy may have been given too late, researchers suggested

An advertisement for lung cancer screening on the back of a kiosk in New York City.

Lung Cancer Screening Rates Remain Low in the U.S., Especially in the South

But one study showed that patient navigation added to usual care may increase uptake

Artery Inflammation and CV Events; Stepped Palliative Care for Lung Cancer Patients

Also in TTHealthWatch: diets and medicine in IBS and active surveillance in prostate cancer

FDA APPROVED imetelstat (Rytelo) over a photo of a bag of blood in blue rubber gloved hands.

Telomerase Inhibitor Approved for MDS-Related Anemia

Imetelstat indicated for lower-risk myelodysplastic syndromes with transfusion-dependent anemia

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Search for Missing Doctor; Energy Drinks and Sudden Death; Unusual Pandemic Cancers

Health news and commentary gathered by 番茄社区 staff

A photo of a female radiologist readying her male patient for radiotherapy.

Near-Perfect Control of Slow-Growing Lymphoma With Low-Dose Radiotherapy

All but four of 24 patients had complete responses to 4 Gy, local control rate of 96% at 3 years

A computer rendering of prostate cancer.

Increased Heart Risks With Newer Prostate Cancer Drugs, Meta-Analysis Shows

Adding ARSIs to ADT for advanced disease doubled the risk of high-grade CV events, death

Onco Break over a computer rendering of a cancer cell.

'Unusual' Cancers After Pandemic; A Win in TNBC; Shortage Pauses Clinical Trial

News, features, and commentary about cancer-related issues

ASCO over a photo of McCormick Place in Chicago, IL

Metformin Fails to Stop Early Prostate Cancer Progression

Study suggests it may even be detrimental in some groups of patients on active surveillance

ASCO over a photo of McCormick Place in Chicago, IL

Docetaxel Tied to Less Taxane Neuropathy in Black Breast Cancer Patients

Dose-limiting toxicity has been linked with worse outcomes specifically in this population

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Star Singer's Illness; AI Imitating the Dead; Internet-Addicted Brains

Health news and commentary gathered by 番茄社区 staff

ASCO over a photo of McCormick Place in Chicago, IL

Adding Isatuximab to Standard Backbone Improves Outcomes in Multiple Myeloma

Two trials show positive outcomes

ASCO over a photo of McCormick Place in Chicago, IL

Neoadjuvant Strategy Establishes Standard of Care for Resectable Stage III Melanoma

A third as many clinical events versus adjuvant therapy, 6 weeks of treatment for many patients

ASCO over a photo of McCormick Place in Chicago, IL

ctDNA Analysis Not Enough to Guide Chemo De-Escalation in Early Pancreatic Cancer

Adjuvant chemo de-escalation based on ctDNA had no effect on recurrence-free survival

ASCO over a photo of McCormick Place in Chicago, IL

A Win for Liver Transplantation in Unresectable Metastatic Colorectal Cancer

Three new trials address CRC liver metastases

ASCO over a photo of McCormick Place in Chicago, IL

New Drug Effective for Tenosynovial Giant Cell Tumors, and With No Liver Concerns

Current option for rare tumor requires a REMS to monitor for drug-induced liver injury

A photo of a male Johnson & Johnson researcher writing chemical formulas on glass with a marker.

Industry Clinic 鈥� Ad Insights

What Will It Take to Deliver Both Health & Care in Oncology?

ASCO over a photo of McCormick Place in Chicago, IL

Dual Immunotherapy Improves Response Rates in Gynecologic Clear Cell Cancers

Clear cell histology "is what yields the super response we see in these trials," expert suggests

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

IRS Sues Controversial Doctor; Congresswoman Has Cancer; Caffeine and Teens

Health news and commentary gathered by 番茄社区 staff

ASCO over a photo of McCormick Place in Chicago, IL

Cheap Drug Eases Hot Flashes in Men With Prostate Cancer

Anticholinergic oxybutynin for patients taking ADT also improved quality of life in the process

ASCO over a photo of McCormick Place in Chicago, IL

Limited-Stage SCLC Gets a New Standard of Care With Consolidation Durvalumab

Median OS was 55.9 months in the durvalumab group compared with 33.4 months in the placebo group

ASCO over a photo of McCormick Place in Chicago, IL

Perioperative Chemo Extends Survival in Resectable Esophageal Cancer

Improvement also observed in complete remission rates with FLOT over CROSS regimen

ASCO over a photo of McCormick Place in Chicago, IL

Lymphadenectomy Not Needed in Advanced Ovarian Cancer With Optimal Surgery

PFS was not significantly different for those who skipped lymphadenectomy

ASCO over a photo of McCormick Place in Chicago, IL

Triplet Notches Survival Win in Heavily Pretreated DLBCL

Benefit with BV plus lenalidomide-rituximab seen in those who relapsed after CAR-T or transplant

ASCO over a photo of McCormick Place in Chicago, IL

Antibody-Drug Conjugate Picks Up Another Win in HR+/HER2-low Breast Cancer

Trastuzumab deruxtecan extended its superiority versus chemotherapy into HER2-ultralow

ASCO over a photo of McCormick Place in Chicago, IL

Novel CD40 Agonist-Chemo Combo Shows Promise in Pancreatic Cancer

Frontline treatment with mitazalimab plus mFOLFIRINOX achieved responses in 40% of patients

ASCO over a photo of McCormick Place in Chicago, IL

'Practice Changing' Trial for Inoperable Locally Advanced NSCLC

EGFR testing now needed for all patients with stage III disease, experts say

ASCO over a photo of McCormick Place in Chicago, IL

Intralesional Therapy for Melanoma Effective, May Have Systemic Activity

Preoperative antibody fusion daromun significantly reduced relapse versus upfront surgery

ASCO over a photo of McCormick Place in Chicago, IL

Blenrep-Based Regimen Yields PFS Benefit in Relapsed/Refractory Myeloma

Second belantamab mafodotin-containing triplet to show potency in this setting

ASCO over a photo of McCormick Place in Chicago, IL

Virtual and In-Person Palliative Care Equally Beneficial in Advanced Lung Cancer

No differences observed in quality of life metric, patient and caregiver satisfaction

ASCO over a photo of McCormick Place in Chicago, IL

Subcutaneous Amivantamab Plus Lazertinib Non-Inferior to IV Dosing in NSCLC

Unexpectedly offers a possible overall survival benefit, researchers say

ASCO over a photo of McCormick Place in Chicago, IL

Novel Bispecific in EGFR-Mutant Lung Cancer Boosts PFS After Targeted Agents

China-based trial may present a hurdle to FDA approval, however

ASCO over a photo of McCormick Place in Chicago, IL

Kinder, Gentler Regimen for Classical Hodgkin Prevails in Randomized Trial

Better efficacy with brentuximab vedotin versus standard chemo, substantially less toxicity

Onco Break over a computer rendering of a cancer cell.

Fewer Suicides in Cancer Patients; Circadian Rhythm Boost; HIV Vaccine for Cancer?

News, features, and commentary about cancer-related issues

A photo of a cytobrush lying on clear rubber gloves next to a sample container.

HPV Testing Outperforms Pap Smear for Detecting Cervical Cancer Precursor Lesions

Rates of cervical intraepithelial neoplasia at 8 years similar to 3-year rates with cytology

ASCO over a photo of McCormick Place, in Chicago, IL

STAMP Inhibitor Tops Imatinib, Second-Gen TKIs for Newly Diagnosed CML

The benefit-risk profile could change the treatment paradigm in CML, expert says

ASCO over a photo of McCormick Place, in Chicago, IL

Unprecedented PFS Results in ALK-Positive Lung Cancer Trial

"We have not seen anything close to this," says expert

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