New Standard for Relapsed/Refractory Multiple Myeloma? Triplet regimen significantly extended median PFS versus doublet in IKEMA study Jun 15, 2020
High Marks for CAR T Cells in R/R Myeloma Response rates of 70-100% with BCMA-targeted products for heavily treated disease Jun 03, 2020
Second Surgery Gets OS Win in Recurrent Ovarian Cancer Survival improved by nearly 8 months with cytoreductive surgery at first relapse Jun 02, 2020
Early Palliation: Boon for AML Patients on Intensive Chemo Intervention led to marked improvements in QoL, mental distress, end-of-life care Jun 02, 2020
Pembrolizumab May Help in Triple-Negative Breast Cancer Upfront therapy extends progression-free survival in metastatic disease, study shows Jun 01, 2020
Surgery for Metastatic Breast Cancer Fails to Boost Overall Survival Cumulative data, though, don't rule out benefit for selected patients with de novo stage IV disease Jun 01, 2020
Add-On Tucatinib Ups Survival in Breast Cancer With Brain Mets TKI plus trastuzumab-capecitabine reduced risk of death by nearly half Jun 01, 2020
VRd Still Reigns in Newly Diagnosed Myeloma KRd fails to prove superiority in head-to-head trial Jun 01, 2020
CAR T-Cell Therapy Impresses in Indolent NHL Overall response rate exceeding 90% with axi-cel in relapsed/refractory setting May 31, 2020
Oral ADT Slashes Heart Risk in Advanced Prostate Cancer Novel GnRH antagonist has potential to be new standard, says researcher May 30, 2020
Studies Make Case for Hormonal Therapy in nmCRPC Prolonged survival with three different androgen signaling inhibitors May 30, 2020
HCQ Linked to Harm in Cancer Patients Combination with azithromycin associated with three-fold risk of mortality, registry study shows May 28, 2020
New First-Line Standard in Metastatic Bladder Cancer "High bar to beat" as avelumab maintenance improves median survival by over 7 months May 28, 2020
Paradigm Shift Coming for Early NSCLC? Postoperative osimertinib doubles DFS in patients with stages Ib-IIIa EGFR+ lung cancer May 28, 2020
End of Life and COVID-19; DCIS Doubles Cancer Risk; Training for 'Bad News' News, features, and commentary about cancer-related issues May 28, 2020
New Clue to Anti-PD-L1 Activity in Breast Cancer? Survival benefit with durvalumab in patients with PDL1 copy number alteration May 26, 2020
Biologics Don't Increase Melanoma Risk... Probably Meta-analysis offers some reassurance, but leaves room for doubt May 20, 2020
Avelumab Flops Again in Ovarian Cancer Another negative phase III trial, now in the first-line setting May 19, 2020
PARP Inhibitors Still Work in HRD-Low Ovarian Cancer In VELIA, homologous recombination deficiency score prognostic but not predictive May 14, 2020
KRAS May Predict Benefit of MEK Inhibitors in Some Ovarian Cancers Nearly 7-month PFS boost in patients with KRAS mutations May 11, 2020
Five Days of G-CSF Adequate for Breast Cancer Chemo Rate of chemotherapy-induced febrile neutropenia similar to 7- to 10-day regimen May 08, 2020
Face-Aging Selfies Help Modify Risky Skin Behaviors for Teens Trial looked at effects of a free "UV-selfie" app May 07, 2020
BMI, Weight Change Linked to Prostate Ca Outcomes Gain or loss of body weight both show risk May 07, 2020
Blood Test Promising as Colorectal Cancer Screen In early study, better numbers than with current alternatives to colonoscopy May 07, 2020
Ranitidine Cancer Risk: Health Records Offer Reassurance Huge study finds no indication that nitrosamine contamination affected real-world outcomes May 05, 2020
Honing Chemo Use in Small Breast Tumors Clearest survival benefit for 8-10 mm tumors in HR/HER2-positive disease May 03, 2020
Nivolumab-Based Tx Effective in Early, Unfavorable Hodgkin's Interim results showed high CR rates and almost 100% PFS, OS at 12 months May 01, 2020
6-Week Keytruda Safe, Effective in Melanoma Schedule gets FDA approval for all adult indications Apr 30, 2020
Talzenna Misses OS Endpoint in BRCA-Positive Breast Cancer But PARP inhibitor improved patient-reported outcomes over standard therapy Apr 29, 2020
COVID-19 Mortality Spikes in Patients With Lung, Blood Cancers Those with metastatic disease also at special risk for poor outcomes Apr 28, 2020
Anti-PD-L1 Plus PARP Inhibitor Ups Response in Breast Cancer Add-on treatment superior to chemo alone, but questions remain about cost, toxicity Apr 28, 2020
Triplet Succeeds in BRAF-Mutant Melanoma Immunotherapy plus BRAF/MEK inhibition boosts PFS over targeted agents alone Apr 27, 2020
Add-On Metformin No Help in Advanced Endometrial Cancer Trial highlights deep racial disparities in treatment response, survival outcomes Apr 27, 2020
Hormone Levels Tied to Future Breast Cancer Risk "New avenues for exploration" in risk stratification Apr 24, 2020
Herceptin Boosts OS in HER2-Positive Uterine Cancer New data bolster targeted approach for aggressive tumor type Apr 24, 2020
New Standard in Recurrent, Platinum-Sensitive Ovarian Cancer Pegylated liposomal doxorubicin unseats gemcitabine in standard platinum regimen Apr 21, 2020
Breastfeeding Tied to Lower Ovarian Cancer Risk Lower incidence of borderline tumors as well Apr 02, 2020
Blood Test Spot On for HPV Cancer Recurrence Near-100% accuracy for ruling in or out recurrent oropharyngeal cancer Apr 01, 2020
