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News, opinions and meeting coverage in oncology/hematology.

A computer rendering of CAR T-cells attacking cancer cells.

Second Malignancy Risk With CAR T-Cell Therapy on Par With Other Treatments

Incidence almost identical to that with standard cancer treatment in randomized trials

A computer rendering of a chronic lymphocytic leukemia cell.

BTK Inhibitor Active in Half of Patients With Richter Transformation

Responses to pirtobrutinib observed in patients with previously treated disease

A photo of a lab technician moving a bag of cultivated hematopoietic stem cells

Mixed Results With Cyclophosphamide in Mismatched Unrelated Stem Cell Transplants

Better survival in one registry study, detriment with class I HLA mismatch in another

A photo of a variety of medications scattered on $100 bills

Is Medicare's Negotiated Drug Price List Worth Celebrating? Depends on Whom You Ask.

Reactions from physician and consumer groups were positive, but drugmakers begged to differ

Onco Break over a computer rendering of a cancer cell.

More Support for Early Detection; Cancer in Men Rising; Diet Drives Colon Cancer

News, features, and commentary about cancer-related issues

Medicare Unveils First 10 Negotiated Drug Prices

Prices slashed by as much as 79%

A computer rendering of parvovirus B19 particles.

CDC Alerts on Dramatic Rise in Human Parvovirus B19

Pregnant people and those who are immunocompromised most at risk, agency warns

Onco Break over a computer rendering of a cancer cell.

No Gestational Diabetes-Cancer Link; Cholesterol and Cancer; Oncologist Saves Umpire

News, features, and commentary about cancer-related issues

Onco Break over a computer rendering of a cancer cell.

Approval in Endometrial Cancer Expanded; Masks at Cancer Centers; NPR Reporter Dies

News, features, and commentary about cancer-related issues

IAC over a photo of Messe M眉nchen in Convention center in Munich, Germany

'Next Berlin Patient' Adds to Small but Growing Number of People Cured of HIV

New case suggests HIV cure can be achieved independent of stem cell transplant donor CCR5 status

A photo of a smiling woman holding a positive pregnancy test.

'Realistic Chance for Pregnancy' After Stem Cell Transplant, German Study Suggests

77% of pregnancies resulted in live births

A photo of a female teen wearing a head scarf being comforted by her mother.

Young Cervical Cancer, Leukemia Survivors at Greater Risk of Obstetric Complications

Population-based study suggests reassurance for most, high-risk strategies for some

Onco Break over a computer rendering of a cancer cell.

EU Adds CAR-T Warning; New Blincyto Indication; Good News in Pancreatic Cancer

News, features, and commentary about cancer-related issues

EHA over a photo of IFEMA Madrid in Spain.

Three-Drug Regimens Make Case for a Role in Untreated and Relapsed/Refractory CLL

Undetectable MRD rates of 90% or higher, PFS of 7 years or more

EHA over a photo of IFEMA Madrid in Spain.

New Standard of Care in High-Risk Acute Promyelocytic Leukemia?

All-trans retinoic acid plus arsenic trioxide and idarubicin improved EFS over standard

A computer rendering of CAR T cell therapy in Diffuse large B-cell lymphoma

New Clues to Origin of T-Cell Lymphoma After CAR-T Therapy

Co-mutations, viral link, potential common susceptibility emerge from two studies

FDA APPROVED imetelstat (Rytelo) over a photo of a bag of blood in blue rubber gloved hands.

Telomerase Inhibitor Approved for MDS-Related Anemia

Imetelstat indicated for lower-risk myelodysplastic syndromes with transfusion-dependent anemia

Onco Break over a computer rendering of a cancer cell.

'Unusual' Cancers After Pandemic; A Win in TNBC; Shortage Pauses Clinical Trial

News, features, and commentary about cancer-related issues

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Star Singer's Illness; AI Imitating the Dead; Internet-Addicted Brains

Health news and commentary gathered by 番茄社区 staff

ASCO over a photo of McCormick Place, in Chicago, IL

STAMP Inhibitor Tops Imatinib, Second-Gen TKIs for Newly Diagnosed CML

The benefit-risk profile could change the treatment paradigm in CML, expert says

Onco Break over a computer rendering of a cancer cell.

Ignoring Colonoscopy Advice; Inflamed Tongue, Then Cancer; Acupuncture for Dry Mouth

News, features, and commentary about cancer-related issues

A close up photo of a woman鈥檚 hand with an IV line attached.

Ending Oncology's Toxic Relationship With High Chemotherapy Doses

Optimizing doses can improve patient outcomes and lower costs

A computer rendering of acute myeloid leukemia cells in the blood.

Venetoclax Combo Safe, Effective in AML Patients Age 80 and Up, Real-World Data Show

Study finds survival is comparable to that seen in younger patients in VIALE-A trial

A photo of a couple holding hands during a meeting with a fertility doctor.

Fresh and Frozen Embryo Transfers May Increase Risk of Childhood Leukemia

However, overall cancer risk was not higher after fertility treatments vs natural conception

Illustration of blood cells with circulating tumor cells.

High Deep-Remission Rate With Triple Regimen for Relapsed/Refractory CLL

Undetectable disease rate over 90%, ctDNA also promising for earlier detection of recurrence

Illustration of an engineered T-cell attacking a leukemia cell.

CAR-T Plus Stem-Cell Transplant Promising for CD7+ Blood Cancers

"All-in-one" approach appears safe, effective, in patients with relapsed/refractory disease

A photo of a pregnant woman napping while receiving chemotherapy.

Immunotherapy During Pregnancy Just as Safe as Other Cancer Drugs

However, use should be avoided "if possible" due to risk of rare immune-related adverse events

A photo of Hezaran Dorna paper cranes laying on a table.

1,000 Paper Cranes Can Bring Our Patients One Step Closer to Healing

We must remind our patients to hold on to hope

Onco Break over a computer rendering of a cancer cell.

Chemo and Heart Disease; Flawed Lung Cancer Screening; New Vax Recommendations

News, features, and commentary about cancer-related issues

A photo of a woman breastfeeding her baby at home.

Breastfeeding Tied to Reduced Childhood Leukemia Risk

Lower pediatric ALL risk in Danish study when mothers exclusively breastfed for 3 months or more

FDA APPROVED ponatinib (Iclusig) over a computer rendering of the destruction of lymphoblast cells

FDA Approves New Frontline Regimen for Aggressive ALL

Ponatinib lands indication in combination with chemo for Philadelphia chromosome-positive cases

Onco Break over a computer rendering of a cancer cell.

Broader Cancer Risk With CAR-T? AI for Physician Burnout; 'Lollipops' ID Oral Cancer

News, features, and commentary about cancer-related issues

A photo of a woman holding a tray of stainless equipment at a medical sterilization facility

EPA Imposes New Limit on Medical Sterilization Chemical, Citing Cancer Risk

Rule would lower emission standards for ethylene oxide by 90%, agency says

FDA APPROVED lisocabtagene maraleucel (Breyanzi) over a computer rendering of CLL cells in the blood stream.

FDA Approves First CAR-T for Chronic Lymphocytic Leukemia

Lisocabtagene maraleucel (Breyanzi) nabs new indication for relapsed or refractory CLL/SLL

FDA ODAC imetelstat (Rytelo) over a close up photo of a person receiving a blood transfusion.

FDA Panel Endorses Imetelstat for MDS-Related Anemia

By 12-2 vote, members find improvement in transfusion independence outweighs risk

Onco Break over a computer rendering of a cancer cell.

Getting Prostate Cancer Drugs Sooner; Limiting Toxic Emissions; FTC Sues 'Charity'

News, features, and commentary about cancer-related issues

FDA ODAC imetelstat (Rytelo) over a close up photo of a person receiving a blood transfusion.

FDA Staff Cast Doubt on Novel Drug for MDS-Related Anemia

Agency asking its advisors if benefits outweigh risks for patients who fail on standard treatment

Onco Break over a computer rendering of a cancer cell.

A Blenrep Comeback? Cancer Vaccine for Dogs; U.K. Snubs Enhertu

News, features, and commentary about cancer-related issues

A computer rendering of acute myeloid leukemia cells in the blood

All-Oral AML Regimen Shows Promise for Older, Unfit Patients

Response rate of 64% in newly diagnosed patients, 46% in those with refractory/relapsed disease

A photo of families holding handwritten signs at a protest outside a sterilization plant in Illinois.

Toxic Gas That Sterilizes Medical Devices Prompts Safety Rule Update

The EPA is set to take action after public outcry

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