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Hypertension

News, opinions and meeting coverage in geriatrics.

Low BP May Be Fatal in CKD

Chronic kidney disease patients, including those with diabetes, who were not on dialysis were more likely to die when blood pressure was too low, even if only on the diastolic measure, a veterans cohort showed.

FDA Adds GI Warning to Benicar Label

WASHINGTON -- The FDA ordered the maker of the blood pressure drug olmesartan (Benicar) to add a warning about risk of the intestinal condition known as sprue-like enteropathy to the drug's label.

Honey, Cola May Disrupt Heart

A detailed history of patients with arrhythmia or syncope might need to include their cola intake or the origin of the honey they consume, two case studies suggest.

ACE Inhibitors Linked to Hallucinations in Elderly

Elderly patients with memory problems who suddenly have visual hallucinations may need to stop taking ACE inhibitors, researchers suggested.

Novel Drug Stars in Phase III PAH Trial

ATLANTA -- Macitentan, a next-generation endothelin receptor antagonist for pulmonary arterial hypertension, met its efficacy endpoint and was said to be well tolerated in a large clinical trial.

BP Drug Linked to Severe Diarrheal Illness

LAS VEGAS -- A patient's insightful question led to the identification of almost two dozen cases of severe enteropathy associated with use of blood pressure medication, investigators reported here.

Cardio Notes: Sex Improves with Stenting

Opening the arteries of those with stable coronary disease also opens the door to an improved sex life. Also this week, bariatric surgery helps remodel the heart.

Watchdog Group Wants Black Box on BP Meds

WASHINGTON -- The consumer watchdog group Public Citizen petitioned the FDA to add a black box warning to three classes of hypertension drugs, cautioning against their combined use.

Cranberry Juice May Help Lower BP a Bit

Cranberry juice modestly lowers blood pressure in healthy adults when consumed daily, a carefully controlled trial showed.

Doctors Say 45 Common Tests 'Overused'

Nine specialty groups have listed tests and treatments that are frequently overused, such as antibiotics for sinus attacks and CT scans for low back pain, in the first phase of a long-term project.

FDA Adds Diabetes Warning to Statin Label

WASHINGTON -- The FDA is changing the labeling on statins to include a warning about increased risks of hyperglycemia and transient memory problems, but the agency is no longer recommending routine liver function testing.

Big BP Variation Between Arms Raises Red Flag

A substantial difference in blood pressure from one arm to the other could be a warning sign for overall cardiovascular and mortality risk, a meta-analysis determined.

Fructose No Substitute for Glucose in Diabetes

NEW YORK -- Although it negates the dumping of glucose directly into the bloodstream, fructose may not be the choice sweetener for diabetics, researchers said here.

Systolic BP That's Too Low After Stroke Not Good Either

Systolic blood pressure that is too low -- as well as too high -- may put patients who have had a noncardioembolic ischemic stroke at risk for another one, researchers found.

High Blood Pressure May Spark Facial Nerve Pain

Patients with hypertension appear to carry a higher risk for developing trigeminal neuralgia, a Taiwanese study showed.

New ARB Cleared for Hypertension Treatment

The FDA has approved azilsartan medoxomil (Edarbi), an oral angiotensin II receptor blocker (ARB) for hypertension, expanding the ranks of ARBs now available to U.S. patients.

Common Antibiotic Linked to Elevated Potassium

Among older individuals, the commonly used antibiotic trimethoprim-sulfamethoxazole (TMP-SMX) is associated with the development of hyperkalemia requiring hospitalization, researchers found.

ASH: Hypertension Plus Tachycardia Equals High Risk

NEW YORK -- An elevated resting heart rate is associated with an increased risk of cardiac events in high-risk hypertension, according to a secondary analysis of a large randomized trial.

ASCO GU: BP Reveals Hit or Miss for Targeted Tx

SAN FRANCISCO -- Early response to preoperative targeted therapy for metastatic renal cell carcinoma may indicate efficacy, while treatment-induced hypertension may be another marker after surgery, according to studies reported here.

Hidden Dangers of Herbal Meds Reviewed

Herbal medicines are not always the harmless nostrums that many patients and even some physicians think, but may actually contribute to cardiovascular morbidity and mortality, researchers warned.

Parents Pass On Hypertension Risk to Their Children

BALTIMORE -- Men whose parents have hypertension are at an increased risk for developing high blood pressure themselves, a longitudinal cohort study showed.

High Blood Pressure Lowers Walking Ability in Elderly

CHICAGO -- High blood pressure appears to impair older patients' ability to walk, and the reason may be more than just peripheral arterial disease.

Drugs That Lower Blood Pressure Also Prevent Headaches

LONDON - Four classes of drugs that lower blood pressure also prevent headaches, say researchers here who analyzed data from 94 randomized, placebo-controlled trials.