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Endocrinology

News, opinions and meeting coverage in endocrinology.

Stinky Diabetes Drug May Result in Poor Adherence

An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

Down a Beer to Improve Bone Health? Not So Fast

A flagon of ale may indeed be a good source of dietary silicon, a recent study showed, but experts say any attempt to link beer drinking to bone health is not based on scientific data.

SSRIs Affect Breast Milk Production

Women taking selective serotonin reuptake inhibitor antidepressants may experience delays in postpartum milk production, researchers said.

The Top 10 Medical Advances of the Decade

From genome to hormones, doctors pick the top medical advances of the decade.

FDA Finds Oral Insulin Spray Safe for IND Use

The FDA approved Oral-lyn, an insulin spray treatment for type I and type II diabetes, for its Investigational New Drug program.

Kidney Disease Raises Risk of Hypoglycemia

WHEELING, W.Va. -- Dangerous hypoglycemic episodes are a significant risk for patients with chronic kidney disease, whether they have diabetes or not, researchers said.

Osteoporosis Drug Speeds Fracture Healing

TORONTO -- A drug for severe osteoporosis has an unexpected side effect, researchers found -- it appears to speed healing of hard-to-mend bone fractures.

Dizziness Linked to Bone Health

SEONGNAM, South Korea -- Low bone mineral density may increase the risk of benign positional vertigo, researchers found.

Weight-Loss Trial Final Report: 52 Pounds of Fat Melted Away

WEST PALM BEACH, Fla. -- The official results are in: My ending weight was 231 pounds -- a loss of 52 pounds from my starting weight of 283 pounds in January 2008.

RSNA: Dry-Needling Plus Steroid Effective for Plantar Fasciitis

CHICAGO -- For patients with plantar fasciitis, a notoriously difficult condition to treat, an Italian team has come up with a novel approach that uses dry-needling combined with a steroid injection, researchers said here.

Recall of Three Little Words Helps Quick Diagnosis of Mild Cognitive Impairment

ATLANTA -- Mild cognitive impairment can be determined in less than five minutes with a three-word memory test and a clock- drawing task, according to researchers here. The words are apple, penny, and table.

Pregnancy Risks Differ for Interracial Couples

STANFORD, Calif. -- The risk for some pregnancy complications may be greater when one partner is white and the other Asian, researchers found.

Normal Enzyme Levels May Hide Advanced Liver Fibrosis

MILAN, Italy -- Patients with nonalcoholic fatty liver disease but normal alanine aminotransferase (ALT) levels are still at risk of severe hepatic disease, researchers found.

Herpes Virus Linked to Ketosis-Prone Diabetes

PARIS -- A herpes virus is associated with an atypical form of type 2 diabetes found in people of African origin, researchers said here.

Excess Weight Unlikely to Be 'Glandular Problem'

LEXINGTON, Ky. -- Correcting the hormonal deficit caused by hypothyroidism did not trigger significant weight loss in children with acquired hypothyroidism.

Boxed Heart Failure Warning Added to Two Diabetes Drugs

ROCKVILLE, Md. -- The makers of rosiglitazone (Avandia) and pioglitazone (Actos), have agreed to add a black box warning to the type 2 diabetes drugs' labels about an increased risk of heart failure, the FDA said today.

ASCO: Five Years of Arimidex Causes Bone Loss

ATLANTA 芒鈧€� Five years of breast cancer adjuvant therapy with an aromatase inhibitor, can lead to a 6% to 7% loss of bone mineral density, a trigger for osteoporosis for women who are borderline osteopenic when they begin treatment, investigators reported here.

High-Dose Steroids Linked to Risk of Atrial Fibrillation

ROTTERDAM, The Netherlands 芒鈧€� High dose corticosteroid therapy may increase the risk of atrial fibrillation, researchers here reported.

Estrogen Alone Does Not Increase Risk of Breast Cancer

STANFORD, Calif. - Post-menopausal women who took estrogen alone for more than seven years did not have an increased risk of breast cancer, according to a study of more than 10,000 women ages 50 to 79. The data were dramatically different from a sister study stopped in 2002 of estrogen plus progestin.

Pediatricians Say Most U.S. Kids Don't Get Enough Calcium

ELK GROVE, Ill. - Most U.S. children don't get enough calcium in their diets, and pediatricians should intervene to help remedy the problem, according to guidelines issued today by the American Academy of Pediatrics.

Corticosteroids Helps Some ICU Patients Off Ventilators Faster

TAPEI, Taiwan - ICU patients with adrenal insufficiency who are on mechanical ventilation are more likely to be successfully weaned off the machine if they first receive hydrocortisone infusions, researchers here have found.

Certain Exercise Proposed to Reduce Hip Fracture Risk in Elderly

CAMBRIDGE, England-If hip fractures in the elderly are caused by thinning of the femur that leads to bone buckling in a fall, as a team here contends, cycling, rowing or gymnastics might strengthen the femoral neck and reduce the fracture risk.

FDA Approves 'Gila Monster' Diabetes Drug

ROCKVILLE, Md.-The FDA announced today it has approved a new injectable diabetes drug synthesized from gila monster saliva, but says the drug should only be used in combination with older oral medications.

Adrenal Suppression From Topical Corticosteroids Surprisingly High

GAITHERSBURG, Md.-Adrenal suppression affects 30% to 80% of users of prescription topical corticosteroids, according to data presented at an FDA advisory panel meeting. The session was convened to discuss taking prescription topical corticosteroids over the counter.