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Critical Care

News, opinions and meeting coverage in critical care.

AHA: No Excess Bleeding Risk with Dabigatran

LOS ANGELES -- Patients starting dabigatran (Pradaxa) did not have a higher risk of bleeding compared with new users of warfarin, according to a postmarketing data review by the FDA.

BP Drug Linked to Severe Diarrheal Illness

LAS VEGAS -- A patient's insightful question led to the identification of almost two dozen cases of severe enteropathy associated with use of blood pressure medication, investigators reported here.

Cardio Notes: Sex Improves with Stenting

Opening the arteries of those with stable coronary disease also opens the door to an improved sex life. Also this week, bariatric surgery helps remodel the heart.

Working with Weights May Help Stroke Rehab

Resistance training -- which is often overlooked in stroke rehab -- may help improve thinking and memory in stroke survivors, researchers found.

Low Preop Sodium Raises Mortality Risk

Preoperative hyponatremia significantly increased the risk of 30-day postsurgical mortality, a risk that extended across all subgroups of surgical patients, investigators reported.

Brain-Eating Amoeba Came From Faucet

The recent cases of primary amoebic meningoencephalitis represent the first reported instances of U.S. tap water harboring the amoeba that causes the fatal disease, according to CDC researchers.

Most ICD Patients Die of Heart Failure

Patients with implantable defibrillators or resynchronization devices with defibrillator were most likely to die of heart failure or non-cardiac causes, not sudden death, a single-center study found.

Brain Bleed Size Affects Therapy in Afib Patients

NEW ORLEANS -- The size of a brain bleed appears to determine which medications, if any, are given to atrial fibrillation patients after an intracerebral hemorrhage, a retrospective study showed.

Doctors Say 45 Common Tests 'Overused'

Nine specialty groups have listed tests and treatments that are frequently overused, such as antibiotics for sinus attacks and CT scans for low back pain, in the first phase of a long-term project.

Renal Function Key in C. Diff Therapy Choice

SAN DIEGO -- Patients with Clostridium difficile infection and underlying impaired renal function fared better with fidaxomicin treatment than with vancomycin, a researcher said here.

Cheney's Heart Makes Him a Million Dollar Man

Keeping former Vice President Dick Cheney's heart beating probably will cost the healthcare system at least a million dollars, cardiac transplantation experts told 番茄社区.

Shire Quits on Fabry Drug

Shire PLC has withdrawn its U.S. application to market an enzyme replacement therapy for Fabry disease, citing an expected FDA demand for controlled clinical trials.

FDA Adds More Warnings for Lipitor, Crestor, and Zocor

WASHINGTON -- Statins may cause drug-drug interactions for patients taking drugs to treat HIV/AIDS or hepatitis C, according to a new statin warning from the FDA.

FDA Adds Diabetes Warning to Statin Label

WASHINGTON -- The FDA is changing the labeling on statins to include a warning about increased risks of hyperglycemia and transient memory problems, but the agency is no longer recommending routine liver function testing.

In Cocaine Users Think About Levamisole

HOUSTON -- Half of a group of cocaine users tested positive for levamisole, a potentially hazardous veterinary drug that cocaine dealers often use to prepare street product, investigators reported here.

Early VTE Therapy OK After Brain Bleed

HOUSTON --The risk of re-bleeding after intracranial hemorrhage did not increase when patients received early prophylaxis for venous thromboembolism (VTE), a retrospective review showed.

Researcher Charged With Fabricating Red-Wine Data

A veteran researcher, known for his work on the heart benefits of the red-grape component resveratrol, allegedly fabricated data in 23 papers published over five years, an investigation showed.

'Brain-Eating' Amoeba Kills Second Neti Pot User

Louisiana state health officials are warning patients about potential dangers of using tap water for sinus irrigation after two patients died of Naegleria fowleri infection.

Breast Reduction Riskier After 50

Outcomes of breast reduction surgery worsen with age, with more infections and a tendency toward wound-healing problems in women older than 50, researchers found.

Systolic BP That's Too Low After Stroke Not Good Either

Systolic blood pressure that is too low -- as well as too high -- may put patients who have had a noncardioembolic ischemic stroke at risk for another one, researchers found.

Life Expectancy Shorter After TIA

Nine years after discharge, the survival of patients hospitalized with a transient ischemic attack was 20% lower than expected, with older patients more likely to be affected, according to an Australian study.

Airport Metal Detectors Safe for Pacemakers

Metal detector security screening appears safe for people with pacemakers or implantable cardioverter-defibrillators (ICDs), researchers found.

Linezolid Toxic With Prozac, Other SSRIs, FDA Warns

The FDA has issued an updated statement on the potential for serious central nervous system toxicity when patients taking serotonergic psychiatric drugs are treated with the antibacterial agent linezolid (Zyvox).

HFSA: Controversy Highlighted at Upcoming Meeting

BOSTON -- Much progress has been made in managing heart failure, but there are still some areas of controversy that will be highlighted at the upcoming meeting of the Heart Failure Society of America here.

Clindamycin Works Better for Skin Infections in Kids

For children with skin and soft tissue infections, clindamycin is the antibiotic of choice for empiric treatment, researchers found.

Level of Diastolic Function Predicts Death

The presence of moderate or severe diastolic dysfunction in patients with preserved systolic function independently predicted mortality, a retrospective study determined.

Japan Stops Some Vaccinations After Deaths

Japanese health officials have suspended the use of two pediatric vaccines as a precaution following the deaths of four young children, according to multiple media reports.

Failure High in Needle Aspiration of Skin Abscesses

Ultrasonographically guided needle aspiration -- a minimally invasive treatment for uncomplicated superficial skin abscesses -- has a failure rate of almost three in four, researchers reported.

Cardiologist Who Revealed Echo Errors Out of a Job

MILWAUKEE -- A cardiologist whose research at a national medical meeting revealed that other doctors at her hospital were misreading a substantial number of diagnostic echocardiograms has been fired by that hospital, the Journal Sentinel and 番茄社区 have learned.

AHA: Rivaroxaban Scores Win While Omega-3 Flops

CHICAGO -- Good news and not so good news about investigational treatments for atrial fibrillation are featured in this exclusive InFocus video report from the American Heart Association meeting.

Artificial Heart Now Sold Online

The maker of the only FDA-approved temporary total artificial heart has opened an online store to take orders for the device and its accessories.

Giving tPA Late: Risk May Outweigh Benefit

Although beneficial within 4.5 hours of stroke onset, administering recombinant tissue plasminogen activator (tPA) beyond that window appears to increase the risk of dying, a pooled analysis of eight clinical trials showed.

Canadian Politician Comes to U.S. for Heart Surgery

The top politician in Canada's easternmost province has set off fireworks by deciding to go to the U.S. for heart surgery.

This Frog Is No Prince

Water frogs appear to be responsible for yet another Salmonella outbreak in the U.S., CDC researchers say.

CT Safety Warnings Follow Radiation Overdose Accident

Reports of stroke patients who were accidentally exposed to eight times the normal radiation dose during diagnostic CT scans at Cedars-Sinai Medical Center in Los Angeles are prompting safety warnings and soul searching in radiology.

Unmasking the Surgical Mask: Does It Really Work?

For a century, the surgical mask has been the symbol of a safe and sanitary medical environment. The problem is that researchers don't really know if that's true.

ICAAC: Surgical Masks Don't Prevent Infection

SAN FRANCISCO -- Consistent use of N95 respirator masks prevents 75% of respiratory infections for high-risk healthcare workers regardless of whether seal against the skin is confirmed, according to the first randomized clinical trial of their efficacy.

Heavy Daily Drinking Boosts Chances of Lethal Brain Hemorrhage

WHEELING, W.Va. -- Fatal hemorrhagic strokes were more than three times as common in men who had at least six drinks a day, researchers found.

Death of Actress Brings Attention to 'Talk and Die' Syndrome

NEW YORK -- Yesterday's death of stage and screen star Natasha Richardson, two days after a seemingly minor spill on a beginners' ski slope, highlighted the difficulties of recognizing and treating head injuries.

Diastolic Dysfunction Predicts Reduced Exercise Capacity

ROCHESTER, Minn. -- Exercise may be good for the heart, but good diastolic function also appears to protect the capacity for exercise, researchers found.

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