SGLT2 Hesitance; Furosemide's Indication Grows; Legal Fight Over Entresto Generic

— Recent developments of interest in cardiovascular medicine

MedicalToday
Cardio Break over a computer rendering of a heart.

From 2022 to 2023, was low in patients with a class Ia recommendation. (Journal of the American College of Cardiology)

In a phase IIa study, the oral drug HU6 resulted in weight loss for patients with obesity-related heart failure with preserved ejection fraction, according to Rivus Pharmaceuticals.

were linked to opposite trends in cardiovascular disease mortality in a prospective cohort study. (JAMA Internal Medicine)

Mounting evidence suggests that are associated with a higher risk for heart failure. (Circulation: Heart Failure)

Furosemide (Furoscix) was granted an indication expansion to treat congestion in adults with , scPharmaceuticals announced.

A federal court declined to block the launch of a generic competitor to Novartis' , though more litigation is pending. (Reuters)

For patients with cardiogenic shock, immediate failed to improve outcomes by 1 year, but patients with advanced hemodynamic compromise seemed to benefit from it in the ECMO-CS trial. (European Journal of Heart Failure)

Cardiac MRI-derived was a predictor of incident heart failure and cardiovascular events. (ESC Heart Failure)

Patients who underwent percutaneous left atrial appendage occlusion had better outcomes if they received rather than dual antiplatelet therapy, according to the small ADALA trial. (JAMA Cardiology)

For survivors of a , the choice of apixaban (Eliquis) or aspirin apparently made no difference in subsequent event risk. (JAMA Neurology)

Pulse Biosciences announced that its technology, developed to treat atrial fibrillation during cardiac surgery, was successful in initial human cases.

Z-drugs for insomnia were generally not linked to cardiovascular harm, but were. (European Journal of Preventive Cardiology)

The was given FDA 510(k) clearance for simultaneous detection of sleep apnea and ECG recording, maker Huxley Medical said.

Pregnant women with obstructive sleep apnea had a reduced risk of gestational hypertension and preeclampsia if they used treatment. (JAMA Network Open)

The link between and cardiovascular risk was supported by a meta-analysis. (Journal of the American Heart Association)

Researchers reported developing a that predicts an individual's risk of major chronic diseases and premature death. (Nature Medicine)

The was validated to help identify ascending aortic dilation and adverse thoracic aortic events. (European Heart Journal)

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    Nicole Lou is a reporter for , where she covers cardiology news and other developments in medicine.