New PAD Guidelines; AHA on Postpartum Care; Exercise Didn't Stop CAC Progression

— Recent developments of interest in cardiovascular medicine

MedicalToday
Cardio Break over a computer rendering of a heart.

Low-dose rivaroxaban (Xarelto), SGLT2 inhibitors, and GLP-1 receptor agonists have entered for the first time. (Circulation)

Recommendations for were released by the American Heart Association, and include monitoring for risk factors during routine pre-conception and interconception care.

An observational cohort study was associated with a long-term risk of arrhythmias. (European Journal of Preventive Cardiology)

Ninerafaxstat, a novel cardiac mitotrope, showed promise in a phase II trial of patients with . (Journal of the American College of Cardiology)

The FDA said that the is under class I recall due to issues with blood leakage and air entry, including two related deaths.

The can be used as a measure of guideline-directed medical therapy intensity in heart failure. (Circulation: Heart Failure)

The manufacturer-agnostic was granted FDA 510(k) clearance, Implicity announced.

A SMART trial substudy found that the Evolut transcatheter aortic valve replacement (TAVR) system was associated with similar clinical outcomes to its competitor Sapien, but also led to . (MassDevice)

Patients on existing were at higher risk of symptomatic intracerebral hemorrhage (ICH) from subsequent stroke thrombolysis, registry data showed. (JAMA Neurology)

No apparent harms were observed from for patients with mechanical valves. (Journal of the American Heart Association)

for 4 to 6 hours showed promise for controlling stroke severity among patients with acute ischemic stroke undergoing endovascular treatment. (Stroke)

A phase III trial on intravenous tenecteplase in the setting of was stopped early for futility and possible harm. (The Lancet)

Researchers developed a smartphone app that can automatically , enabling downstream machine learning-based diagnostics. (Heart)

Elixir Medical announced that 2 years into the BIOADAPTOR trial, the device demonstrated a reduction in target lesion failure compared with a conventional drug-eluting stent.

Exercising frequently after age 40 did not stop the , a cohort study found. (JAMA Cardiology)

Patients with stable coronary artery disease have a substantial but significantly lower 5-year rate of subsequent cardiovascular death or non-fatal heart attack compared with those with risk factors. (European Heart Journal)

Like adults, children with out-of-hospital cardiac arrest may not benefit from as opposed to continued on-scene CPR. (JAMA Network Open)

A Massachusetts hospital will pay $24.3 million to resolve healthcare fraud allegations related to insufficient evaluation of patients , the Department of Justice said.

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    Nicole Lou is a reporter for , where she covers cardiology news and other developments in medicine.