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Allergy & Immunology

News, opinions and meeting coverage in allergy and immunology.

ATS over a photo of San Diego Convention Center

Add-On Dupilumab for COPD Backed by Second Phase III Trial

NOTUS study confirms fewer exacerbations with biologic for patients on maximum inhaled therapy

ATS over a photo of San Diego Convention Center

Beta-Blocker Fails to Prevent COPD Exacerbations

However, trial results don't affirm safety risks suggested by other studies

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Finding Undiagnosed Asthma, COPD and Treating It Shows Benefit in Trial

Healthcare utilization for respiratory illness halved while quality of life, symptoms improved

A photo of an asthma inhaler.

Study Offers Clues on Asthma Control for Patients With Concurrent Diabetes

Compared with metformin, some newer diabetes agents linked with more acute exacerbations

FDA APPROVED mavorixafor (Xolremdi) over a photo of warts on a woman鈥檚 hand.

FDA Approves First Drug for WHIM Syndrome

CXCR4 antagonist mavorixafor effectively boosts neutrophils and lymphocytes to reduce infections

Close-up shot of pediatrician giving baby intramuscular injection in arm.

Antibiotics in Infancy Tied to Higher Risk for Atopic Dermatitis

An increased number of antibiotic courses corresponded to a dose-response-like increased risk

Night view of a burn pit and a military heavy transport truck.

More Cases of Asthma, COPD, Hypertension After Military Burn Pit Exposure

Ask veterans with symptoms if they were deployed to bases with open burn pits, says expert

A screenshot of a new CDC/National Weather Service color-coded heat warning graphic

When Red-Hot Isn't Enough: CDC's Heat Risk Tool Sets Magenta as Most Dangerous Level

Heat is the number one cause of weather-related death

The advertisement for this live Instagram event.

IG Live April 22: Temperature Rising, Health Declining

How health professionals can help confront climate change

A photo of Zahida 鈥淩ani鈥� Maskatia, MD

New Consensus Recs for Oral Immunotherapy in Food Allergies

Allergist Zahida Maskatia, MD, shares how the guidelines will change practice

A photo of a positive COVID test lying atop several negative tests.

COVID Infection Not Linked to New Asthma Diagnoses in Kids

Less exposure to respiratory viruses, other asthma risk factors during pandemic may have helped

FDA APPROVED benralizumab (Fasenra) over a computer rendering of an inflamed bronchial tube.

FDA Expands Approval of Severe Asthma Drug

Add-on maintenance therapy benralizumab now indicated for children ages 6 to 11 years as well

A photo of a woman browsing produce for sale at a grocery store

New WIC Rules Include More Money for Fruits, Veggies, and Expand Food Choices

Update did not add peanut products to foods allowed, a request by top allergists

A photo of a pregnant woman sitting on a couch and smoking a cigarette.

Why Do Kids of Smokers Wheeze Less When Mom Took Vitamin C During Pregnancy?

Outcomes appear to be mediated by vitamin C's effect on improved airway function

Which Food Allergy Patients Will Benefit Most From Omalizumab?

Bruce J. Lanser, MD, discusses determining who the best candidates are

A photo of traffic at the exit of the Jones Falls Expressway in Baltimore, Maryland.

Can You Guess Which New EPA Rule Offers $13 Billion in Annual Health Benefits?

The new clean car standards provide health and climate benefits alike

Can Machine Learning Predict CVD Risk? Sleep-Related Benefits of Exercise

Also in TTHealthWatch: molnupiravir in immunocompromised people with COVID

Lung Function Improvements Tied to Better Asthma Control in Children

"Yet another motivator for therapies to maximize lung function"

'Major Advance' in Food Allergy Management: Experts Weigh in on OUtMATCH Data

"We're at the beginning of the next era of food allergy management"

Benralizumab Proves Effective for Eosinophilic Granulomatosis With Polyangiitis

More patients in MANDARA trial were able to stop oral corticosteroids than with mepolizumab

FDA APPROVED fluticasone propionate (Xhance) over a computer rendering of a transparent head with the sinuses highlighted.

First Treatment Approved for Chronic Rhinosinusitis Without Nasal Polyps

Daily sprays of Xhance reduced acute exacerbations by 56% to 66% in trials

A photo of tree pollen on the fingers of a man who just dragged them across the side of his car.

Are Your Patients' Allergies Worsening? Climate Change May Be at Play

Taking action, no matter how small, matters

A photo of a neti pot

Another Dangerous Amoeba Linked to Neti Pots and Nasal Rinsing

"These infections are very serious and even life threatening," said CDC physician

Three Trials Examine Dupilumab in Moderate-to-Severe Asthma

Our roundtable of experts discuss the VESTIGE, QUEST, and TRAVERSE trials

AAAAI over a photo of Walter E. Washington Convention Center in Washington, DC

AAAAI Roundup: Perioperative Assessment of Antibiotic Allergy With a Mobile App

Plus, other selected poster presentations from the allergy meeting

Medicaid Expansion and Healthcare Workers; Cardiac Rehabilitation

Also in TTHealthWatch: cognition and memory after COVID

AAAAI over a photo of Walter E. Washington Convention Center in Washington, DC

Epinephrine Nasal Spray Starts Reversing Allergic Reactions in Minutes

After FDA rejection, needle-free EpiPen alternative bolsters its case with small challenge study

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Peanut Allergen Sensitization Seen in Younger Siblings of LEAP Study Participants

If peanuts were introduced in the first year of life, however, this effect was reduced

AAAAI over a photo of Walter E. Washington Convention Center in Washington, DC

Indoor Pest Exposures Tied to Respiratory Issues in Kids With Asthma

Mice, cockroach allergens associated with upper respiratory infections with reduced lung function

AAAAI over a photo of Walter E. Washington Convention Center in Washington, DC

Novel Antibody for Chronic Hives Brings Relief in Mid-Stage Trial

Urticaria severity reduced within weeks of treatment

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Oral Drug Gains Steam as On-Demand Option for Hereditary Angioedema Attacks

Investigational sebetralstat offered symptom relief in under 2 hours

AAAAI over a photo of Walter E. Washington Convention Center in Washington, DC

Dupilumab Cuts Lung Inflammation, Breaks Up Mucus Plugs in Asthma Patients

In VESTIGE trial, IL-4/IL-13 blocker also improved airway volumes and airflow

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Asthma Control Better With Biologic-Corticosteroid Combo

Post hoc data showed durable benefits over high-dose corticosteroid alone

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Drug Slashes Risk of Severe Allergic Reactions to Multiple Foods

Benefits with omalizumab shown for patients with nut, milk, egg, and wheat allergies

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Benralizumab Matches Mepolizumab for Rare Vasculitis

Similar rates of patients with eosinophilic granulomatosis with polyangiitis achieved remission

FDA APPROVED omalizumab (Xolair) over a photo of a syringe and vial laying on and next to a pile of peanuts

First Drug OK'd for Reducing Allergic Reactions From Multiple Foods

68% of patients who received omalizumab tolerated a single dose of peanut after 16-20 weeks

A photo of an Australian family of five sitting on their lawn.

Female Reproductive Factors Linked to COPD Risk

Age at menarche and menopause, number of children seem to play a role

FDA APPROVED budesonide oral suspension (Eohilia) over a computer rendering of a body with the esophagus highlighted.

FDA Approves First Oral Option for Eosinophilic Esophagitis

Fixed-duration course of corticosteroid indicated for patients 11 years and up

A photo of nasal decongestants for sale at a CVS pharmacy.

Phenylephrine Sales Steady Before FDA Panel Called It Ineffective

But reformulation of products containing OTC "decongestant" could affect the supply chain

A photo of a woman clutching her stomach while eating a piece of bread

Does the QoL Impact of Food Allergies Affect Girls, Women More?

Female patients and caregivers report worse QoL scores than male counterparts, review finds

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